A 52-year-old woman suffering from hypertension still had a blood pressure of 156/92 mm Hg after 3 months of therapy with hydrochlorothiazide and losartan. Her physician decided to add a third drug that acts by decreasing central sympathetic outflow. Which of the following adverse effects was most likely to occur after a few days of therapy with the new drug?

Correct Answer: A

Rationale: The most likely adverse effect to occur after adding a third drug that acts by decreasing central sympathetic outflow would be severe postural hypotension. This is due to the combined effect of the drugs leading to a significant drop in blood pressure upon standing up, causing dizziness and potential fainting episodes. This adverse effect is commonly associated with antihypertensive medications that affect sympathetic outflow.

Correct Answer: C

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.