A 5-year-old male patient’s parents complain of recurring fever in their son over the course of a month. Past medical history is significant for easy bruisability. A CBC reveals a white blood cell count of 30,000 cells per microliter. A bone marrow biopsy confirms the diagnosis of acute lymphoblastic leukemia. This child is started on a chemotherapeutic regimen. Which of the following chemotherapy drugs interferes with DNA synthesis after its metabolite is incorporated into the growing DNA strand?

A 5-year-old male patient’s parents complain of recurring fever in their son over the course of a month. Past medical history is significant for easy bruisability. A CBC reveals a white blood cell count of 30,000 cells per microliter. A bone marrow biopsy confirms the diagnosis of acute lymphoblastic leukemia. This child is started on a chemotherapeutic regimen. Which of the following chemotherapy drugs interferes with DNA synthesis after its metabolite is incorporated into the growing DNA strand?

A 47-year-old woman with a rheumatoid arthritis comes to clinic for her annual visit. Her arthritis has not worsened over the past 6 months since starting on infliximab. Her arthritis is worst in the joints of her hands. After her morning stiffness ceases, she can usually go through the rest of the day with minimal pain. What is the mechanism of action of infliximab?

A 37-year-old man with a schizophrenia presents to the emergency room with worsening symptoms. He has been hearing voices in his head that tell him to hurt other people. He is scared by these thoughts and wants help. He is currently taking risperidone. The physician changes him to clozapine. What should the physician monitor while the patient is taking clozapine?

A 46-year-old woman with chronic pelvic pain caused by endometriosis consults a pain management specialist regarding options for treatment. Which of the following statements is true regarding chronic pain management in this patient?

When comparing the effects of overdose of meperidine and morphine in the emergency department evaluation of patients, which of the following features would be characteristic of meperidine overdose?