A 5-year- old boy presented with abdominal mass, hematuria and hypertension. Of the following, the MOST likely diagnosis is

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Infectious Disease Pediatric Questions

Question 1 of 5

A 5-year- old boy presented with abdominal mass, hematuria and hypertension. Of the following, the MOST likely diagnosis is

Correct Answer: A

Rationale: Wilms' tumor commonly presents with an abdominal mass, hematuria, and hypertension due to renin secretion.

Question 2 of 5

Hemorrhagic cystitis is a complication of which of the following chemotherapeutic agents?

Correct Answer: D

Rationale: Cyclophosphamide’s metabolite, acrolein, irritates the bladder, causing hemorrhagic cystitis.

Question 3 of 5

Which of the following classes of chemotherapeutics carries a particular risk for the development of future leukemia?

Correct Answer: D

Rationale: Topoisomerase II inhibitors (e.g., etoposide) are linked to secondary leukemias, particularly AML.

Question 4 of 5

CNS involvement should be excluded at the time of diagnosis of acute lymphoblastic leukemia by

Correct Answer: B

Rationale: Lumbar puncture with CSF analysis is the standard method to detect CNS involvement in ALL.

Question 5 of 5

Which of the following features labels a patient with acute lymphoblastic leukemia as a low risk patient?

Correct Answer: D

Rationale: t(12;21) is associated with a favorable prognosis, classifying the patient as low risk.

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