A 5-year- old boy presented to the emergency department with sudden onset of skin ecchymoses and single attack of epistaxis, the history is negative for any significant event except for preceding upper respiratory tract infection. The examination showed an active healthy looking boy with diffuse skin petechial rash and ecchymoses over both lower and upper limbs, no lymphadenopathy and no organomegaly. The initial CBC is as follows: Hb 12.3 gm/dl, WBC 7.600/cmm, N 45%, L 51%, plt 17.000/cmm, and normal looking film except for rarely seen platelets. The most likely diagnosis is:

A 5-year- old boy presented to the emergency department with sudden onset of skin ecchymoses and single attack of epistaxis, the history is negative for any significant event except for preceding upper respiratory tract infection. The examination showed an active healthy looking boy with diffuse skin petechial rash and ecchymoses over both lower and upper limbs, no lymphadenopathy and no organomegaly. The initial CBC is as follows: Hb 12.3 gm/dl, WBC 7.600/cmm, N 45%, L 51%, plt 17.000/cmm, and normal looking film except for rarely seen platelets. The most likely diagnosis is:

One of the following factors is not available in cryoprecipitate

A 70-year-old man presents with weakness of his right arm and leg. His symptoms began yesterday and are now resolved. He also reports a 6-month history of recurrent headaches and fatigue. He is a nonsmoker. His medical history is significant for high blood pressure. His blood pressure is 167/88 mm Hg, his oxygen saturation is 93% on room air, his face is plethoric, and a right carotid bruit is heard. Other findings on physical examination are normal. Diagnostic testing results are shown in Table 9.Q5. Carotid ultrasonography shows a 30% stenotic lesion in the right carotid. The patient is hospitalized and begins antiplatelet therapy. Which of the following should you order next?

A 20-year-old white woman has been admitted to the hospital with pulmonary embolism. She has no chronic illnesses and is receiving no medications except for combination estrogen-progesterone birth control pills that she started using approximately 1 year earlier. Results were normal for a complete blood cell count, baseline prothrombin time, activated partial thromboplastin time (aPTT), and tests of kidney and liver function. The patient is currently receiving therapeutic doses of intravenous unfractionated heparin, and her aPTT is therapeutic at 72 seconds. A panel of thrombophilia tests has been performed. Which of the following statements about her thrombophilia test results is correct?

Ten years ago, a previously healthy 20-year-old woman presented to her physician with a 2-month history of pruritis, drenching night sweats, unintentional weight loss, and nonproductive cough. On examination, she had 2-cm cervical lymphadenopathy. A computed tomographic scan showed a 12-cm-diameter anterior mediastinal mass. An excisional biopsy of a cervical lymph node showed nodular sclerosing Hodgkin lymphoma. After she was treated with ABVD (doxorubicin [Adriamycin], bleomycin, vinblastine, and dacarbazine) combination chemotherapy followed by involved field radiotherapy, the disease was in complete remission. Now you see her for the first time for an annual physical examination. The disease remains in complete remission. Compared to her peers, this patient is at increased risk of which of the following conditions?