A 5-year-old boy develops hepatosplenomegaly and lymphadenopathy since early onset childhood with high spiking fevers and been treated with anti-inflammatory drugs. You suspect macrophage activation syndrome (MAS). The BEST test that distinguishes MAS from a flare of the primary disease is

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Question 1 of 5

A 5-year-old boy develops hepatosplenomegaly and lymphadenopathy since early onset childhood with high spiking fevers and been treated with anti-inflammatory drugs. You suspect macrophage activation syndrome (MAS). The BEST test that distinguishes MAS from a flare of the primary disease is

Correct Answer: D

Rationale: Hemophagocytosis in the bone marrow is the hallmark of MAS.

Question 2 of 5

Mushrooms of the genus Inocybe contain muscarine or muscarine-related compounds. These quaternary ammonium derivatives bind to postsynaptic receptors, producing an exaggerated cholinergic response. Of the following, the MOST serious complication is

Correct Answer: D

Rationale: Bronchospasm is the most severe muscarinic toxicity, leading to respiratory compromise.

Question 3 of 5

The following signs are more in favor of circulatory failure Except:

Correct Answer: B

Rationale: Marked tachypnea with recessions is more indicative of respiratory failure rather than circulatory failure.

Question 4 of 5

Which of the following is a common feature of Still's disease?

Correct Answer: D

Rationale: Still's disease is characterized by fever, rash, and arthritis, making 'All of the above' the correct answer.

Question 5 of 5

The MOST common clue of physical abuse in children is

Correct Answer: A

Rationale: A history of inflicted trauma is the most direct indicator of physical abuse, though bruises and burn marks are also common signs. Intestinal injury is less frequent and typically indicates severe internal trauma.

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