A 5-month-old infant presented with reluctance to feed, lethargy, abdominal distension, and severe gingivitis. The parents are healthy relatives and give history of non-purulent omphalitis with separation of umbilical stump at the age of 2 months. His peripheral smear showed neutrophil count 24,000/mm3. Of the following, the MOST effective life saving measure is

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Pediatric Immunization NCLEX Questions Ricci Questions

Question 1 of 5

A 5-month-old infant presented with reluctance to feed, lethargy, abdominal distension, and severe gingivitis. The parents are healthy relatives and give history of non-purulent omphalitis with separation of umbilical stump at the age of 2 months. His peripheral smear showed neutrophil count 24,000/mm3. Of the following, the MOST effective life saving measure is

Correct Answer: C

Rationale: Stem cell transplantation corrects leukocyte adhesion deficiency, addressing the underlying genetic defect for long-term survival.

Question 2 of 5

CD4 in secondary lymphoid organs that has not been exposed to its antigen yet is called?

Correct Answer: C

Rationale: Naïve mature T helper cells (CD4+) reside in secondary lymphoid organs before antigen exposure, distinguishing them from activated or cytotoxic cells.

Question 3 of 5

which of the following is not in LPS recognition pathway

Correct Answer: D

Rationale: CD46 regulates complement, not LPS recognition, which involves CD14, MD2, and MYD88 in the TLR4 pathway.

Question 4 of 5

Which of the following doesn't Express MHC II

Correct Answer: A

Rationale: Neutrophils do not express MHC class II, unlike professional APCs (macrophages, B cells, dendritic cells) or activated endothelial cells.

Question 5 of 5

Which immune cell is responsible for the quickest release of histamine that causes the red itchy welts associated with allergies?

Correct Answer: A

Rationale: Mast cells rapidly release histamine in allergic responses, causing welts.

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