ATI RN
CNS Stimulants Drugs Pharmacology Quiz Questions
Question 1 of 5
A 49-year-old man with long-standing schizophrenia is hospitalized for a symptom exacerbation. His primary care physician places him on a second-generation antipsychotic agent. Characteristics of this agent include which of the following?
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 2 of 5
Symptoms of acute morphine toxicity include:
Correct Answer: A
Rationale: Acute morphine toxicity, an overdose scenario, presents a classic triad: coma, pinpoint pupils (miosis), and depressed respiration (choice A). Coma results from profound CNS depression, miosis from parasympathetic overstimulation, and respiratory depression from medullary suppression, often fatal without intervention (e.g., naloxone). Abdominal cramps and diarrhea (choice B) suggest withdrawal, not toxicity. Hypertension and arrhythmias (choice C) align with stimulants, not opioids. Dry mouth and mydriasis (choice D) are anticholinergic signs, opposite to morphine's effects. This triad is critical for rapid diagnosis and treatment in emergency settings, distinguishing opioid toxicity from other syndromes.
Question 3 of 5
The following are useful in management of an acute attack of gout EXCEPT:
Correct Answer: A
Rationale: Acute gout attacks require rapid inflammation reduction. Colchicine (choice B) disrupts microtubule function, reducing neutrophil activity. Indomethacin (choice C), an NSAID, inhibits COX, lowering prostaglandin levels. Glucocorticoids (choice D) suppress inflammation broadly. Allopurinol (choice A), a xanthine oxidase inhibitor, lowers uric acid long-term but doesn't address acute inflammation, making it the exception. This distinction guides acute versus chronic gout management.
Question 4 of 5
The following drugs are useful in management of gout EXCEPT:
Correct Answer: A
Rationale: Colchicine (choice B) treats acute gout by reducing inflammation, Allopurinol (choice C) lowers uric acid long-term, and Sulphinpyrazone (choice D) promotes urate excretion. Thiazide diuretics (choice A) increase uric acid retention, worsening gout, making them the exception. This distinguishes gout management from contraindicated drugs.
Question 5 of 5
Drugs useful to initiate sleep include which of the following:
Correct Answer: D
Rationale: Flurazepam (choice A), Triazolam (choice B), and Chlordiazepoxide (choice C), all benzodiazepines, initiate sleep via GABAa potentiation, differing in duration (long, short, intermediate). ‘All of the above' (choice D) is correct, as each is a hypnotic, tailored to insomnia needs, highlighting benzodiazepine versatility.