A 49-year-old man with advanced squamous cell carcinoma of the skin is treated with topical 5-fluorouracil. He presents to his oncologist for follow-up. In addition to monitoring renal and hepatic function for toxicity, one could theoretically measure levels of which of the following excreted products?

A 49-year-old man with advanced squamous cell carcinoma of the skin is treated with topical 5-fluorouracil. He presents to his oncologist for follow-up. In addition to monitoring renal and hepatic function for toxicity, one could theoretically measure levels of which of the following excreted products?

A 4-year-old boy is brought by his mother to the clinic complaining of perianal itching. He spends the weekdays at a daycare center. The mother also brings a strip of adhesive tape from the night before which she had stuck to the child’s perianal area as the doctor had ordered on the phone. Microscopic examination of the tape revealed small, white, round worms. Which is the best treatment for this child?

A 31-year-old woman with HIV disease complains of vulvar itching, burning, and vaginal discharge with rancid odor for 2 months. She presents to the ambulatory care clinic for evaluation. She has had unprotected sexual intercourse with multiple male partners during the past several weeks. The vaginal discharge is yellow-green in color, frothy, and has a pH of 7.0. Vulvovaginal examination reveals vulvar edema and erythema and petechia on the cervix. Wet smear reveals large numbers of mature epithelial cells, white blood cells, and a fusiform protozoan organism. What is the most appropriate treatment for this patient?

A 34-year-old woman complains of fever, fatigue, weight loss, arthralgia, and transient patchy alopecia during the last 3 months. Her review of systems is notable for occasional rhinorrhea and cough that responds well to oral decongestant therapy. Her prior surgical history is notable for cesarean section and tubal ligation at age 31 years. A similar constellation of symptoms occurred 6 months ago during treatment for a cardiovascular disease. Antinuclear antibody testing was positive at her last visit 6 months ago and is still positive at the present time. Presently, her hematocrit is 36% and creatinine is 1.2 mg/dL. The most likely etiology of this constellation of symptoms and findings is related to

A 41-year-old man with a history of gastroesophageal reflux disorder and diabetes mellitus is managed with cimetidine and diet/exercise for these disorders. The fact that he takes cimetidine means that the treating physician must be attune to increased effects of which of the following drugs?