A 48-year-old man with schizophrenia on thioridazine for 20 years develops bilateral facial and jaw movements and rhythmic motions of his tongue. Physical examination of the heart, lungs, and abdomen are unremarkable. What is the most likely aberration on a neurotransmitter level?

A 48-year-old man with schizophrenia on thioridazine for 20 years develops bilateral facial and jaw movements and rhythmic motions of his tongue. Physical examination of the heart, lungs, and abdomen are unremarkable. What is the most likely aberration on a neurotransmitter level?

A 47-year-old woman is recovering from a hysterectomy. Her physician prescribes an opioid analgesic as needed for postoperative pain. Opioids can cause many effects in addition to analgesia including constipation, respiratory depression, euphoria, miosis, and drowsiness. With prolonged use, tolerance develops to most of these effects. Which of the following effects persists in spite of tolerance leading to a decrease in the other effects?

A novel medication to treat gastric motility disorders will act at the terminal step in the synthesis/breakdown of acetylcholine. Which of the following is the terminal step in the synthesis and release of acetylcholine?

Stimulation of inhibitory neurons causes which of the following effects at the postsynaptic membrane?

An 8-year-old boy presents to the emergency department after seizure-like activity. During class, the teacher noted that the boy stare off for about 45 s. He has done this three times in the past. He would not respond to her during the episode and was confused for about 1 min following it. What is the most appropriate first-line therapy for this child?