A 47-year-old patient came to see a doctor on the 7th day of disease. The disease developed very fast: after the chill body temperature rose to 40oC and lasted up to 7 hours, then dropped abruptly, which caused profuse sweat. There were three such attacks occur in once in two days. Two days ago the patient arrived from Africa. Objectively: pale skin, subicteric sclera, significantly enlarged liver and spleen. What is the cause of fever attacks in this disease?

Correct Answer: A

Rationale: The correct answer is A: Erythrocytic schizogony. In this case, the patient most likely has malaria, specifically caused by Plasmodium falciparum. The fever attacks every 2 days (tertian fever) are characteristic of P. falciparum infection. The cycle of erythrocytic schizogony in P. falciparum is around 48 hours, leading to the recurring fever pattern. Choices B, C, and D are incorrect as tissue schizogony does not cause the characteristic fever pattern, exotoxins are not typically involved in malaria fever, and gametocytes do not directly cause fever attacks.

Correct Answer: A

Rationale: The correct answer is A: Clostridium botulinum and Clostridium tetani. Both bacteria produce exotoxins that affect the nervous system. Clostridium botulinum produces botulinum toxin, causing botulism, leading to muscle paralysis. Clostridium tetani produces tetanospasmin, causing tetanus, leading to muscle stiffness and spasms. Choice B (Escherichia coli and Salmonella) are known for causing gastrointestinal infections, not specifically affecting the nervous system. Choice C (Bacillus anthracis and Listeria monocytogenes) produce toxins that primarily affect other body systems, not the nervous system. Choice D (Pseudomonas aeruginosa and Staphylococcus aureus) are associated with skin and respiratory infections, not neurological effects.

Correct Answer: C

Rationale: The correct answer is C: Thermophiles. Thermophiles are bacteria that thrive in high temperatures, typically between 45-80 degrees Celsius. They have adapted to extreme heat environments and have enzymes that function optimally at high temperatures. Mesophiles (A) grow best at moderate temperatures, Psychrophiles (B) thrive in cold temperatures, and Halophiles (D) thrive in high salt concentrations. Therefore, only Thermophiles are specifically adapted to high temperatures, making it the correct choice.

Correct Answer: B

Rationale: The correct answer is B: Endoplasmic reticulum. Prokaryotic cells lack membrane-bound organelles like the endoplasmic reticulum, which is present in eukaryotic cells. Prokaryotes do possess ribosomes for protein synthesis (A), a chromosome (C) for genetic material, and peptidoglycan (D) in their cell walls. The absence of endoplasmic reticulum is a key characteristic that distinguishes prokaryotic cells from eukaryotic cells.

Correct Answer: A

Rationale: The correct answer is A: Viruses. Viruses are acellular, meaning they lack cellular structure, protein synthesizing ability, enzymes, and energy systems. They are essentially genetic material (DNA or RNA) enclosed in a protein coat. Fungi (B), bacteria (C), and protozoa (D) are all cellular organisms with protein synthesizing, enzyme, and energy systems. Viruses rely on host cells to replicate and carry out metabolic functions, making them distinct from other groups.

Correct Answer: B

Rationale: The correct answer is B: The generation time of bacteria refers to the time for a cell to divide and double in number. This is because the generation time is the period required for one bacterial cell to undergo binary fission and divide into two identical daughter cells. This process involves DNA replication, followed by cell division, resulting in an increase in the number of bacterial cells. Incorrect choices: A: The time for DNA replication - While DNA replication is a crucial part of bacterial growth and reproduction, it does not solely define the generation time. C: The time for spore formation - Spore formation is a specific process in certain bacteria and is not synonymous with the generation time. D: The time for toxin production - Toxin production is an independent process in bacteria and does not directly relate to the generation time.

Correct Answer: B

Rationale: The correct answer is B: Herpangina. Family Parvoviridae includes Parvovirus B19, which causes Fifth disease, aplastic crisis in chronic anemia, and fetal infections. Herpangina is caused by Enteroviruses, not Parvoviridae. Parvovirus B19 specifically targets erythroid progenitor cells, leading to anemia in susceptible individuals. Fetal infections can result in hydrops fetalis. Aplastic crisis occurs in patients with chronic anemia due to suppression of erythropoiesis by the virus.

Correct Answer: A

Rationale: The correct answer is A: TRUE. The innate immune system is the body's first line of defense against infections and is always active, providing immediate protection without prior exposure to a specific pathogen. It includes physical barriers, such as skin and mucous membranes, and cellular components like phagocytes and natural killer cells. The innate immune response is nonspecific and rapid, providing a crucial initial defense against pathogens. Choice B is incorrect because the innate immune system is always active, even without any prior exposure to pathogens. Choice C is incorrect because the innate immune system is consistently functioning to protect the body, regardless of the situation. Choice D is incorrect as the correct answer is A.

Correct Answer: D

Rationale: The correct answer is D: All of the above. Clostridium botulinum, Salmonella enterica, and Escherichia coli are all common bacteria associated with food poisoning. Clostridium botulinum produces a potent neurotoxin causing botulism. Salmonella enterica causes salmonellosis, a common foodborne illness. Escherichia coli can produce toxins leading to food poisoning. Therefore, since all three bacteria are known to cause food poisoning, the correct answer is D. Choices A, B, and C are incorrect because each of these bacteria individually is commonly associated with food poisoning, not just one of them.