A 47-year-old patient came to see a doctor on the 7th day of disease. The disease developed very fast: after the chill body temperature rose to 40oC and lasted up to 7 hours, then dropped abruptly, which caused profuse sweat. There were three such attacks occur in once in two days. Two days ago the patient arrived from Africa. Objectively: pale skin, subicteric sclera, significantly enlarged liver and spleen. What is the cause of fever attacks in this disease?

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Question 1 of 9

A 47-year-old patient came to see a doctor on the 7th day of disease. The disease developed very fast: after the chill body temperature rose to 40oC and lasted up to 7 hours, then dropped abruptly, which caused profuse sweat. There were three such attacks occur in once in two days. Two days ago the patient arrived from Africa. Objectively: pale skin, subicteric sclera, significantly enlarged liver and spleen. What is the cause of fever attacks in this disease?

Correct Answer: A

Rationale: The correct answer is A: Erythrocytic schizogony. In this case, the patient most likely has malaria, specifically caused by Plasmodium falciparum. The fever attacks every 2 days (tertian fever) are characteristic of P. falciparum infection. The cycle of erythrocytic schizogony in P. falciparum is around 48 hours, leading to the recurring fever pattern. Choices B, C, and D are incorrect as tissue schizogony does not cause the characteristic fever pattern, exotoxins are not typically involved in malaria fever, and gametocytes do not directly cause fever attacks.

Question 2 of 9

In order to prevent wound infection associated with surgical procedures a patient was given a synthetic antiprotozoan drug with a high activity against Helicobacter pylori. Specify this drug:

Correct Answer: A

Rationale: The correct answer is A: Metronidazole. Metronidazole is a synthetic antiprotozoan drug with high activity against Helicobacter pylori, a bacterium that can cause wound infections. Metronidazole specifically targets anaerobic bacteria like H. pylori, making it effective in preventing wound infections. Incorrect choices: B: Doxycycline hydrochloride - Doxycycline is primarily used for bacterial infections, not protozoan infections like H. pylori. C: Chingamin - Chingamin is not a commonly used drug for treating H. pylori infections or preventing wound infections. D: Acyclovir - Acyclovir is an antiviral drug used to treat herpes infections, not bacterial or protozoan infections like H. pylori.

Question 3 of 9

A patient complains of frequent bowel movements and stool with blood admixtures ("raspberry jelly" stool). Microscopic examination revealed large mononuclear cells with absorbed red blood cells. What protozoon is this morphological structure typical for?

Correct Answer: A

Rationale: The correct answer is A: Entamoeba histolytica. This protozoon is responsible for causing amoebic dysentery, which presents with bloody diarrhea. The "raspberry jelly" appearance of stool is due to the presence of mucosal lining and blood. The large mononuclear cells with absorbed red blood cells are characteristic of the histopathology of Entamoeba histolytica infection. Giardia lamblia (B) causes watery diarrhea, not bloody stools. Campylobacter jejuni (C) is a bacterial pathogen associated with gastroenteritis, but does not typically cause bloody diarrhea. Toxoplasma gondii (D) causes toxoplasmosis, a systemic infection with symptoms such as fever and lymphadenopathy, but not bloody diarrhea.

Question 4 of 9

Which bacteria are commonly associated with food poisoning?

Correct Answer: A

Rationale: The correct answer is A: Clostridium botulinum and Staphylococcus aureus. Clostridium botulinum produces a potent neurotoxin causing botulism, commonly associated with improperly canned foods. Staphylococcus aureus produces toxins causing symptoms of food poisoning. Bacillus anthracis and Mycobacterium tuberculosis are not typically associated with food poisoning. Treponema pallidum and Neisseria gonorrhoeae are bacteria causing sexually transmitted infections. Escherichia coli and Klebsiella pneumoniae are not directly linked to food poisoning.

Question 5 of 9

Enriched growth media:

Correct Answer: B

Rationale: The correct answer is B because enriched growth media provide essential nutrients that support the growth of target bacteria groups without inhibiting the growth of other microorganisms. This allows for the selective cultivation of specific microbes while still allowing for the growth of other organisms present in the sample. Choice A is incorrect because enriched media do not belong to minimal media and do not inhibit the development of gram+ cocci. Choice C is incorrect because enriched media can support the growth of multiple microbial species. Choice D is incorrect because enriched media do not suppress the development of other microorganisms but rather provide nutrients to support their growth alongside the target bacteria groups.

Question 6 of 9

Which type of bacteria can survive in extreme salty environments?

Correct Answer: B

Rationale: The correct answer is B: Halophiles. Halophiles are bacteria that can survive in extreme salty environments. They have adapted to thrive in high salt concentrations. Psychrophiles (A) thrive in cold temperatures, Thermophiles (C) thrive in high temperatures, and Mesophiles (D) thrive in moderate temperatures. Therefore, they are not adapted to survive in extreme salty environments like Halophiles.

Question 7 of 9

How would you interpret the study results?

Correct Answer: D

Rationale: Step-by-step rationale: 1. The study results indicate water contamination. 2. Contaminated water poses health risks. 3. Therefore, the correct interpretation is that water is contaminated. Summary: - Choice A is incorrect as safety is not confirmed. - Choice B is too mild given the severity of contamination. - Choice C is also incorrect, as it does not accurately reflect the study findings.

Question 8 of 9

Urine examination of a patient with acute cystitis revealed leukocytes and a lot of gram-negative bacilli. Inoculation resulted in growth of colonies of mucous nature that formed green soluble pigment. What microorganism is the most probable cause of the disease?

Correct Answer: C

Rationale: Rationale: 1. Presence of gram-negative bacilli suggests Enterobacteriaceae family, which includes E. coli. 2. Green soluble pigment indicates pyocyanin production, characteristic of E. coli. 3. E. coli is the most common cause of acute cystitis due to its ability to colonize the urinary tract. Summary: A: Pseudomonas aeruginosa is not typically associated with acute cystitis and does not produce mucous colonies. B: Klebsiella pneumoniae may cause UTIs, but does not produce green pigment and is less common than E. coli. D: Salmonella enteritidis is associated with gastrointestinal infections, not cystitis.

Question 9 of 9

Which of the following viral infections can result in chronic carrier state.

Correct Answer: D

Rationale: The correct answer is D: All of these. HBV, HCV, and HDV can all lead to chronic carrier states due to their ability to establish persistent infections in the liver. HBV can result in chronic hepatitis, cirrhosis, and even liver cancer. HCV can also lead to chronic hepatitis and liver damage. HDV is a defective virus that requires HBV for replication and can worsen the outcome of HBV infection, potentially leading to chronic liver disease. Therefore, all three viruses have the potential to cause chronic carrier states.

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