ATI RN
Pharmacology of CNS Drugs Questions
Question 1 of 5
A 47-year-old man presents with acute pain in his big toe. Lab tests reveal a serum uric acid level of 10 mg/dl. After treatment for the acute attack he was shifted to a drug that decreases both serum and urine level of uric acid. This drug is:
Correct Answer: A
Rationale: Allopurinol (choice A) reduces serum and urinary uric acid by inhibiting xanthine oxidase, preventing urate formation, ideal for chronic gout post-acute attack. Colchicine (choice B) and Indomethacin (choice C) treat acute inflammation, not uric acid levels. Probenecid (choice D) increases urinary uric acid excretion, not decreasing it. Allopurinol fits the description for long-term gout management.
Question 2 of 5
Which of the following is not a pharmacologic effect of morphine:
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
All the following are regarded as antiepileptic (anticonvulsant) drugs, EXCEPT:
Correct Answer: C
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 4 of 5
Both the older (tricyclic) antidepressants and the newer ones (e.g. fluoxetine) relieve signs and symptoms of depression mainly by doing which one of the following things?
Correct Answer: C
Rationale: TCAs (e.g., imipramine) and SSRIs (e.g., fluoxetine) (choice C) block reuptake of serotonin and/or norepinephrine, increasing synaptic levels to treat depression. Blocking receptors (choice A, B) or stimulating serotonin (choice D) aren't primary mechanisms. Reuptake inhibition is their shared action.
Question 5 of 5
Selective serotonin reuptake inhibitors (SSRI) do NOT include:
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.