ATI RN
Introduction to the Pharmacology of CNS Drugs Questions
Question 1 of 4
A 47-year-old man exhibited signs and symptoms of acromegaly. Radiologic studies showed the presence of a large pituitary tumor. Which of the following drugs is most likely to be used as pharmacologic therapy?
Correct Answer: D
Rationale: Octreotide (choice D), a somatostatin analog, treats acromegaly by inhibiting growth hormone from pituitary tumors, reducing symptoms. Cosyntropin (choice A) tests adrenal function, Desmopressin (choice B) manages diabetes insipidus, Leuprolide (choice C) targets sex hormones. Octreotide is specific.
Question 2 of 4
A patient with severe shoulder pain resulting from inflammation is not responding to treatment with naproxen. You elect to begin a course of treatment with oral dexamethasone. What is the basis that the glucocorticoid will be more effective as an anti-inflammatory agent?
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 4
Men who use large doses of anabolic steroids are at increased risk of:
Correct Answer: D
Rationale: Large doses of anabolic steroids (choice D) risk liver toxicity, including cholestatic jaundice and elevated AST, due to hepatic metabolism and 17-alpha-alkylated forms. Anemia (choice A) isn't typical (erythrocytosis occurs), testicular enlargement (choice B) reverses to atrophy, and hirsutism (choice C) is female-specific. Liver damage is a serious concern, necessitating monitoring in steroid abuse scenarios.
Question 4 of 4
A 58 year-old postmenopausal woman has low bone mineral density. Chronic use of which of the following medications is most likely to have contributed to this woman's osteoporosis?
Correct Answer: C
Rationale: Prednisone (choice C), a glucocorticoid, contributes to osteoporosis by inhibiting osteoblasts and increasing resorption, a common chronic use effect. Lovastatin (choice A), Metformin (choice B), and Propranolol (choice D) don't significantly affect bone density. Prednisone's impact is well-documented.