ATI RN
Endocrine Pharmacology Quiz Questions
Question 1 of 5
A 45-year-old man has high serum LDL and low serum HDL. He presents to his primary care physician for treatment guidance. In addition to exercise and diet modification, which of the following agents would provide him with the most efficacious improvement of serum LDL and HDL levels?
Correct Answer: D
Rationale: Simvastatin, a statin, effectively lowers LDL and modestly raises HDL, outperforming bile acid sequestrants like cholestyramine in dual lipid improvement.
Question 2 of 5
A 62-year-old female with diabetes presents to her primary care physician for follow-up. She takes pioglitazone daily and her blood sugar ranges approximately from 100 to 180mg\dL. Which of the following indicators would likely have minimal or no change from baseline values with this therapy?
Correct Answer: C
Rationale: Pioglitazone, a PPAR-gamma agonist, improves insulin sensitivity but does not significantly alter insulin levels, unlike glucose or HbA1c, which improve with better control.
Question 3 of 5
A 20-year-old woman becomes pregnant out of wedlock and wants to terminate the pregnancy with an oral abortifacient. The use of mifepristone (RU-486) as an oral abortifacient is based on which of the following characteristics?
Correct Answer: B
Rationale: Mifepristone is a progesterone receptor antagonist, blocking progesterone's support of pregnancy, leading to uterine shedding and abortion.
Question 4 of 5
A 32-year-old woman with endometriosis of the uterus, pelvic sidewall, and bladder has chronic unrelenting pelvic pain. She is prescribed with danazol. Over the next few weeks, she experiences a 40% improvement in her symptoms. What physiologic changes are likely to be found in this patient as a result of this medication?
Correct Answer: D
Rationale: Danazol, a synthetic androgen, suppresses FSH and LH, reducing estrogen-driven endometrial growth, alleviating endometriosis symptoms.
Question 5 of 5
A 49-year-old woman with a history of hypertension is treated with spironolactone. She has good blood pressure control and in the last 6 months has shown an improvement in her hirsutism. What is the most likely explanation for these findings?
Correct Answer: A
Rationale: Spironolactone, an aldosterone antagonist, also inhibits androgen receptors, reducing hirsutism by decreasing androgen effects on hair follicles.