ATI RN
ATI Pharmacology Study Guide PDF Questions
Question 1 of 5
A 44-year-old man with acute lymphocytic leukemia is undergoing a multiagent chemotherapy protocol. Agents used include methotrexate. The cycle of medication will last 6 weeks. Which of the following tissues is most likely to experience toxic effects as a result of this therapy?
Correct Answer: A
Rationale: Methotrexate targets rapidly dividing cells. Buccal mucosa , with high turnover, is most vulnerable, causing mucositis. Bones (B, D) and skin are less affected. Teeth (E) aren't primary. This toxicity reflects methotrexate's antimetabolite action in ALL.
Question 2 of 5
The pregnant patient plans to breastfeed her baby. She asks the nurse about the use of herbal products during breastfeeding. What is the best response by the nurse?
Correct Answer: B
Rationale: Herbals (e.g., St. John's wort) transfer to breast milk, risking infant effects (e.g., sedation), so avoiding them is safest, per pharmacokinetics. Labels lack consistent breastfeeding data. ‘Natural' doesn't mean safe-some are toxic. Timing doesn't eliminate transfer. Transfer risk advises caution, protecting the baby.
Question 3 of 5
What is one therapeutic use for Nitroglycerine?
Correct Answer: A
Rationale: Nitroglycerine is commonly used as a therapeutic agent for the relief or prevention of anginal attacks in patients with stable angina or chronic angina pectoris. Angina is a condition characterized by chest pain or discomfort that occurs when the heart muscle does not receive enough oxygen-rich blood. Nitroglycerine works by dilating blood vessels, which helps to increase blood flow to the heart and reduce the workload of the heart, thereby relieving chest pain associated with angina.
Question 4 of 5
What is the priority outcome for a 6-year-old patient who had been started on methylphenidate (Ritalin)?
Correct Answer: D
Rationale: Methylphenidate for ADHD risks appetite suppression-maintaining weight is priority, per side effect monitoring, as growth lags can occur. Avoiding fights, chores, and play improve but aren't immediate risks. Weight reflects health impact, key in kids.
Question 5 of 5
When teaching a patient who has a new prescription for transdermal nitroglycerin patches, the nurse tells the patient that these patches are most appropriately used for which situation?
Correct Answer: C
Rationale: Transdermal nitroglycerin patches are primarily used for the prevention and management of angina pectoris, a condition characterized by chest pain or discomfort due to reduced blood flow to the heart. Nitroglycerin works by dilating the blood vessels, which helps to improve blood flow to the heart muscle and reduce the workload on the heart. By preventing angina episodes, nitroglycerin patches can help to alleviate chest pain, improve exercise tolerance, and enhance the overall quality of life for patients with angina. It is not used to prevent low blood pressure, relieve shortness of breath, or control heart rate during exercise.