A 43 y.o. patient was admitted to the hospital with complaints of high temperature of the body and severe headache. On examination: carbuncle is revealed on the forearm. There are intense edema around it, insignificant pain, regional lymphadenitis. The patient is a worker of cattle-ranch. What disease is it necessary to think about first?

Correct Answer: D

Rationale: The correct answer is D: Erysipeloid. Erysipeloid is a bacterial infection caused by Erysipelothrix rhusiopathiae commonly found in animals like cattle. The patient's occupation as a cattle-ranch worker puts them at risk for this infection. Symptoms such as high body temperature, severe headache, carbuncle on the forearm with edema, and regional lymphadenitis are typical of erysipeloid. Anthrax (A) is more associated with skin lesions and severe systemic symptoms. Carcinoma of skin (B) presents differently with slow-growing skin lesions. Erysipelas (C) is a different bacterial infection characterized by red, swollen patches on the skin.

Correct Answer: C

Rationale: The correct answer is C: ensure survival under harsh conditions. Bacterial endospores are dormant, resistant structures that form under adverse conditions to protect the bacterial DNA and allow the bacterium to survive extreme environments. This function is crucial for the bacterium's long-term survival. Choice A is incorrect as endospores do not directly produce exotoxins. Choice B is incorrect as endospores do not store nutrients but rather protect the bacterium's genetic material. Choice D is incorrect as endospores do not enhance motility but rather enable survival during unfavorable conditions.

Correct Answer: A

Rationale: The correct answer is A: Trichomonas vaginalis. Trichomonas vaginalis is a sexually transmitted protozoan that causes trichomoniasis. The pear-shaped flagellated protozoa with an undulating membrane described in the question match the morphology of Trichomonas vaginalis. It is typically found in vaginal discharge of infected individuals. Giardia lamblia (B) is a different protozoan that causes giardiasis and has a distinct morphology of a teardrop shape with flagella. Trypanosoma brucei (C) causes African sleeping sickness and Leishmania donovani (D) causes visceral leishmaniasis, both of which have different morphologies and clinical presentations compared to Trichomonas vaginalis.

Correct Answer: C

Rationale: The correct answer is C because transcription is the process in which messenger RNA transcripts are produced from DNA. During transcription, a specific segment of DNA is transcribed into mRNA by RNA polymerase. Choice A is incorrect because translation, not transcription, involves converting mRNA into protein. Choice B is incorrect as it describes DNA replication, not transcription. Choice D is incorrect because it refers to translation, where polypeptides are synthesized from mRNA. Therefore, choice C is the correct answer as it accurately describes the process of transcription.

Correct Answer: A

Rationale: Step-by-step rationale: 1. Metronidazole is a synthetic antiprotozoal drug commonly used for wound infection prevention. 2. It is highly effective against Helicobacter pylori, a bacterium that causes stomach ulcers. 3. Metronidazole works by disrupting DNA structure in bacteria, leading to their death. 4. Chingamin (Chloroquine) is an antimalarial drug, not effective against Helicobacter pylori. 5. Doxycycline hydrochloride is an antibiotic used for bacterial infections, not specifically for H. pylori. 6. Aciclovir is an antiviral drug used for herpes infections, not effective against H. pylori. Summary: Metronidazole is the correct answer as it is specifically effective against H. pylori and commonly used for wound infection prevention. Other choices are incorrect as they target different types of infections.

Correct Answer: D

Rationale: The correct answer is D. Botulism typically presents with symptoms such as dry mouth, difficulty swallowing, blurred vision, diplopia, and descending flaccid paralysis. Chills, fever, and loss of consciousness are not typical of botulism. Botulism is caused by a neurotoxin produced by Clostridium botulinum bacteria, which affects the nervous system leading to muscle weakness and paralysis, not fever or altered consciousness. Therefore, choice D is the correct answer.

Correct Answer: D

Rationale: The bacitracin sensitivity test is used to differentiate between different types of streptococci. Group A streptococci are sensitive to bacitracin, which means they will show inhibition around the bacitracin disk. This sensitivity is a characteristic feature of group A streptococci and helps in their identification. Staphylococci, pneumococci, and intestinal bacteria do not exhibit this sensitivity to bacitracin. Therefore, the correct answer is D: group A streptococci.

Correct Answer: A

Rationale: The correct answer is A: Clostridium botulinum. This bacterium produces the neurotoxin responsible for botulism. It thrives in anaerobic environments like improperly canned foods. Clostridium difficile (B) causes colitis, not botulism. Staphylococcus aureus (C) causes food poisoning but not botulism. Escherichia coli (D) can cause gastrointestinal illness but not botulism.

Correct Answer: B

Rationale: The correct answer is B: Neisseria gonorrhoeae. This bacterium is known to cause gonorrhea, a sexually transmitted infection. Neisseria gonorrhoeae specifically infects the mucous membranes of the reproductive tract in both men and women. It is transmitted through sexual contact. Explanation of other choices: A: Chlamydia trachomatis is a bacterium that causes chlamydia, not gonorrhea. C: Mycoplasma genitalium is associated with non-gonococcal urethritis, not gonorrhea. D: Treponema pallidum is the bacterium that causes syphilis, not gonorrhea. Therefore, Neisseria gonorrhoeae is the correct answer based on its direct association with causing gonorrhea.