ATI RN
Chemotherapy drugs Questions
Question 1 of 5
A 42-year-old woman who recently immigrated to the United States from Africa presents with diffuse abdominal pain and an unusual rash. The erythematous linear rash spreads from her right upper quadrant to the umbilicus. Laboratory testing confirms the diagnosis of Toxocara canis infection. What is the most appropriate treatment?
Correct Answer: C
Rationale: Mebendazole is effective against Toxocara canis (visceral larva migrans), inhibiting microtubule formation in the nematode, treating abdominal pain and rash.
Question 2 of 5
A 24-year-old sexually active woman presents with vaginal itching and a greenish, frothy vaginal discharge. Her boyfriend is asymptomatic. She is prescribed with metronidazole for Trichomonas infection. Which of the following is involved in metronidazole’s action?
Correct Answer: B
Rationale: Metronidazole disrupts DNA in anaerobic organisms like Trichomonas vaginalis by forming reactive intermediates, leading to cell death.
Question 3 of 5
A 27-year-old man has been hospitalized with fatigue and feeling sick for the past 4 months. After many tests and labs, an HIV test is performed and comes back positive. His HIV viral load is 36,000 and CD4 count is 369. He is started on multidrug therapy for his HIV disease. One of the drugs is raltegravir. What is the mechanism of action of raltegravir?
Correct Answer: C
Rationale: Raltegravir, an integrase inhibitor, prevents HIV DNA integration into the host genome, a key step in viral replication.
Question 4 of 5
The following precautions about tetracycline use are true EXCEPT:
Correct Answer: D
Rationale: Tetracyclines are contraindicated in pregnancy and early childhood due to effects on teeth and bones, making D the incorrect precaution.
Question 5 of 5
The long-acting penicillin applied for chemoprophylaxis of rheumatic fever as a monthly injection is:
Correct Answer: D
Rationale: Benzathine penicillin is used as a monthly injection for rheumatic fever prophylaxis due to its long-acting depot formulation.