ATI RN
Endocrine Pharmacology Quizlet Questions
Question 1 of 5
A 42-year-old man is a habitual coffee drinker of caffeinated products. Chronic use of this product has led to his addiction. What is the most likely mechanism of action of caffeine?
Correct Answer: D
Rationale: Caffeine inhibits adenosine receptors (not guanosine), increasing alertness by blocking inhibitory adenosine signaling; 'thymine receptors' is likely a typo.
Question 2 of 5
A 29-year-old man with a family history of heart disease comes to your office for a routine checkup. A lipid profile on a blood draw reveals high LDL and low HDL. One way to decrease the amount of LDL in the blood is to hinder intestinal absorption of cholesterol. Which of the following drugs blocks brush border enzymes to inhibit intestinal absorption of cholesterol?
Correct Answer: D
Rationale: Ezetimibe inhibits NPC1L1 on intestinal brush borders, reducing cholesterol absorption and lowering LDL.
Question 3 of 5
A 62-year-old man has developed worsening hypertension in spite of therapy. His physician wants to prescribe an additional medication that will dilate his blood vessels to help lower his blood pressure. Which of the following is a calcium channel blocker that affects vascular smooth muscle and cardiac muscle equally well?
Correct Answer: B
Rationale: Diltiazem, a non-dihydropyridine CCB, equally affects vascular smooth muscle (vasodilation) and cardiac muscle (negative inotropy/chronotropy).
Question 4 of 5
A 43-year-old woman with Type-2 diabetes has been taking insulin with meals as well as metformin. Her blood glucose remains poorly controlled. Her doctor prescribes an additional drug, which is an analog of an endogenous peptide that enhances insulin secretion. What drug is this?
Correct Answer: A
Rationale: Exenatide, a GLP-1 analog, enhances glucose-dependent insulin secretion, aiding control in Type-2 diabetes.
Question 5 of 5
A 34-year-old man presents to his primary care physician because of an enlarging jaw and hands over the past 6 months. He has noticed enlargement of most his facial features, including his jaw, forehead, nose, and tongue. His hands have gotten bigger as well. He is diagnosed with acromegaly. What is the most appropriate treatment for this patient?
Correct Answer: C
Rationale: Octreotide, a somatostatin analog, inhibits GH secretion in acromegaly, reducing feature enlargement.