ATI RN
Endocrine Pharmacology Quiz Questions
Question 1 of 5
A 41-year-old man with end-stage HIV disease has lost approximately 50lb from his baseline weight of 160lb. He now weighs in the fifth percentile for his age group. He is given dronabinol to achieve a change in this area. The most plausible mechanism of action for this medication is
Correct Answer: A
Rationale: Dronabinol, a cannabinoid, stimulates appetite via CB1 receptors in the hypothalamus, addressing weight loss in HIV wasting syndrome.
Question 2 of 5
A 72-year-old man with congestive heart failure is hospitalized because of worsening pulmonary and peripheral edema. He is given intravenous furosemide. This agent will likely improve hemodynamics in which of the following ways?
Correct Answer: A
Rationale: Furosemide, a loop diuretic, reduces preload by decreasing venous return through diuresis, alleviating edema and improving CHF hemodynamics.
Question 3 of 5
A 52-year-old man is prescribed with furosemide by his physician to help treat his hypertension. His physician further advises him to avoid NSAIDs for pain because they may antagonize the effects of furosemide. Which of the following describes how NSAIDs may interfere with the effects of furosemide?
Correct Answer: C
Rationale: NSAIDs inhibit prostaglandin synthesis, which normally enhances furosemide's natriuretic effect; this leads to increased sodium reabsorption, reducing furosemide's efficacy.
Question 4 of 5
A 45-year-old man has high serum LDL and low serum HDL. He presents to his primary care physician for treatment guidance. In addition to exercise and diet modification, which of the following agents would provide him with the most efficacious improvement of serum LDL and HDL levels?
Correct Answer: D
Rationale: Simvastatin, a statin, effectively lowers LDL and modestly raises HDL, outperforming bile acid sequestrants like cholestyramine in dual lipid improvement.
Question 5 of 5
A 39-year-old man with insulin-dependent diabetes mellitus is brought to the emergency department after collapsing in a shopping mall. His blood sugar is 589mg\dL. Which of the following preparations would have the least minimal effect on his blood sugar levels?
Correct Answer: B
Rationale: Insulin glargine, a long-acting insulin, has a slow onset and minimal immediate effect on acute hyperglycemia compared to rapid-acting insulins like aspart, lispro, or regular.