ATI RN
Microbiology A Systems Approach Test Bank Questions
Question 1 of 9
A 40 year old man noticed a reddening and an edema of skin in the area of his neck that later developed into a small abscess. The incised focus is dense, yellowish-green. The pus contains white granules. Histological examination revealed drusen of a fungus, plasmatic and xanthome cells, macrophages. What type of mycosis is the most probable?
Correct Answer: D
Rationale: The correct answer is D: Sporotrichosis. Sporotrichosis is caused by the fungus Sporothrix schenckii, which commonly presents as a subcutaneous infection. In the given case, the presence of a small abscess with yellowish-green pus containing white granules is indicative of sporotrichosis. The histological examination showing drusen of a fungus, plasmatic and xanthome cells, and macrophages further supports the diagnosis of sporotrichosis. Choice A: Actinomycosis is a bacterial infection caused by Actinomyces species, not a fungal infection. Choice B: Aspergillosis is caused by Aspergillus species and typically presents as a pulmonary infection, not a subcutaneous abscess as described in the case. Choice C: Candidosis is caused by Candida species and usually presents as mucocutaneous infections, not a subcutaneous abscess with the
Question 2 of 9
Which one is true for enteropathogenic E.coli?
Correct Answer: A
Rationale: The correct answer is A because enteropathogenic E. coli (EPEC) have fimbrial adhesins that help them bind to enterocytes in the intestines, leading to colonization and infection. This is a key virulence factor of EPEC. Explanation for why other choices are incorrect: B: EPEC typically cause watery diarrhea in infants, not bloody diarrhea similar to shigellosis. C: EPEC are not part of the normal intestinal flora; they are pathogenic bacteria. D: EPEC are not invasive and do not typically produce enterotoxin; they primarily adhere to the intestinal epithelium.
Question 3 of 9
Acute febrile pharyngitis and pharyngoconjunctival fever are often the clinical presentation of which viral infection:
Correct Answer: D
Rationale: The correct answer is D: Adenovirus. Adenovirus commonly causes acute febrile pharyngitis and pharyngoconjunctival fever. Adenovirus is known to cause respiratory infections and can present with symptoms such as sore throat, fever, and conjunctivitis. VZV (Varicella-Zoster Virus) causes chickenpox and shingles, not these specific symptoms. Measles virus causes a systemic illness with characteristic rash, not typically pharyngitis. Rubella virus causes a mild febrile illness with rash, but not pharyngitis. Therefore, based on the clinical presentation described, adenovirus is the most likely cause.
Question 4 of 9
What is the primary purpose of a bacterial capsule?
Correct Answer: C
Rationale: The correct answer is C: Enhancing virulence by preventing phagocytosis. Bacterial capsules help bacteria evade the immune system by preventing phagocytosis, a process where immune cells engulf and destroy pathogens. This enhances the bacteria's virulence and ability to cause infections. Choices A, B, and D are incorrect because bacterial capsules do not directly contribute to protein synthesis, protect against desiccation, or facilitate motility.
Question 5 of 9
What is the role of coagulase in bacteria like Staphylococcus aureus?
Correct Answer: C
Rationale: The correct answer is C because coagulase helps bacteria like Staphylococcus aureus to form clots, allowing them to evade the host immune response. This mechanism helps the bacteria to hide from the immune system and establish infection. A. Adhesion to surfaces is usually facilitated by other factors like adhesins. B. Breaking down red blood cells is not a function of coagulase. D. Antibiotic resistance is typically mediated by other mechanisms like efflux pumps or enzymatic inactivation, not coagulase.
Question 6 of 9
Which of the following bacteria is known for causing the disease known as leprosy?
Correct Answer: A
Rationale: Step-by-step rationale: 1. Mycobacterium leprae is the correct answer as it is the bacteria known to cause leprosy. 2. Clostridium perfringens is incorrect as it is associated with gas gangrene. 3. Streptococcus pneumoniae is incorrect as it is commonly linked to pneumonia and meningitis. 4. Neisseria gonorrhoeae is incorrect as it causes gonorrhea, a sexually transmitted infection. In summary, Mycobacterium leprae is the only bacteria among the choices specifically known to cause leprosy, making it the correct answer.
Question 7 of 9
Which of the following bacteria is responsible for causing syphilis?
Correct Answer: A
Rationale: Step 1: Treponema pallidum is a spirochete bacterium known to cause syphilis. Step 2: It is sexually transmitted and can cause various stages of disease. Step 3: Neisseria gonorrhoeae causes gonorrhea, not syphilis. Step 4: Chlamydia trachomatis causes chlamydia, not syphilis. Step 5: Escherichia coli is a common gut bacterium and not responsible for syphilis. Treponema pallidum is the correct answer as it is the specific bacterium known to cause syphilis.
Question 8 of 9
Which of the following consists of DNA viruses?
Correct Answer: A
Rationale: The correct answer is A: Parvoviridae. Parvoviruses are DNA viruses, as their genetic material is composed of DNA. This distinguishes them from RNA viruses like Picornaviridae, Astroviridae, and Togaviridae. Parvoviruses replicate in the host cell nucleus, further confirming their DNA nature. Therefore, based on their DNA composition and replication process, Parvoviridae is the correct choice.
Question 9 of 9
What is the name of the enzyme that allows the bacteria to become resistant to most penicillins?
Correct Answer: C
Rationale: The correct answer is C: Beta lactamase. This enzyme is produced by bacteria to break down the beta-lactam ring structure of penicillins, rendering them ineffective. Beta lactam ring (A) is part of the penicillin molecule, not an enzyme. MRSA (B) stands for methicillin-resistant Staphylococcus aureus, a type of bacteria resistant to certain antibiotics, not an enzyme. Aminoglycoside ring (D) refers to a different class of antibiotics and is not related to penicillin resistance in bacteria.