A 40-year-old female farmworker has been diagnosed with brucellosis and administered causal chemotherapy. What group of drugs will be used for this purpose?

Correct Answer: A

Rationale: The correct answer is A: Antibiotic. Brucellosis is a bacterial infection, and antibiotics are the primary treatment to target and eliminate the bacteria causing the disease. Antibiotics such as doxycycline and rifampin are commonly used for brucellosis treatment. Donor immunoglobulin (B) is not used to treat brucellosis as it is not caused by a deficiency in antibodies. Inactivated therapeutic vaccine (C) is used for prevention, not for treating active infections. Antitoxic serum (D) is used to neutralize toxins produced by bacteria, not to directly kill the bacteria themselves in cases like brucellosis.

Correct Answer: A

Rationale: Step-by-step rationale: 1. Arenaviridae family includes viruses with a segmented genome. 2. Lassa virus has a segmented genome, placing it in the Arenaviridae family. 3. Crimean-Congo hemorrhagic fever virus belongs to the Nairoviridae family, not Arenaviridae. 4. Rabies virus belongs to the Rhabdoviridae family, not Arenaviridae. 5. Epstein-Barr virus belongs to the Herpesviridae family, not Arenaviridae. Summary: A: Lassa virus is correct because it has a segmented genome, characteristic of Arenaviridae. B, C, D: Crimean-Congo hemorrhagic fever virus, Rabies virus, and Epstein-Barr virus belong to different virus families, not Arenaviridae.

Correct Answer: A

Rationale: The correct answer is A: Bacillus anthracis. The presence of Gram-positive rods in chains with central spores on the Gram stain indicates Bacillus anthracis. This bacterium is known to cause severe pneumonia. Clostridium tetani does not typically cause pneumonia but rather tetanus. Streptococcus pneumoniae is a Gram-positive cocci, not rods. Klebsiella pneumoniae is a Gram-negative bacterium commonly associated with pneumonia, but it does not form central spores.

Correct Answer: A

Rationale: The correct answer is A because growth factors are essential nutrients that bacteria cannot synthesize on their own and must obtain from the environment for their growth. Bacteria rely on these external factors for processes like cell division, metabolism, and survival. Choice B is incorrect because bacteria can only synthesize growth factors in limited amounts, not sufficient for their growth. Choice C is incorrect as bacterial cells do not store growth factors in granules. Choice D is incorrect because bacterial cells do not synthesize growth factors in large amounts.

Correct Answer: B

Rationale: The correct answer is B: sporadic disease. Infection of several persons without any epidemiological link is considered sporadic because it occurs in a random and isolated manner, with no clear pattern or connection between cases. It is not classified as an epidemic (A) because it does not involve a sudden increase in the number of cases within a specific population. It is also not endemic (C) as endemic diseases are constantly present in a particular region or population. Lastly, it is not a pandemic (D) which refers to a global outbreak affecting a large number of people across different countries.

Correct Answer: D

Rationale: The correct answer is D. Cytoplasmic inclusions in bacteria refer to substances like granules. These granules can be excess products of metabolism or reserve substances stored for future use. Therefore, all of the choices are correct as cytoplasmic inclusions can be any of these substances. A is correct as it directly refers to cytoplasmic inclusions. B is correct as some granules can be excess metabolic products. C is correct as certain granules can serve as reserve substances. Therefore, the correct answer is D, as it encompasses all the possible types of substances found as cytoplasmic inclusions in bacteria.

Correct Answer: D

Rationale: The correct answer is D: Immunocomplex. In this case, the patient's symptoms of fever, joint pains, rash, and itch along with leukopenia and thrombocytopenia indicate a serum sickness reaction. This is a type III hypersensitivity reaction where antigen-antibody complexes deposit in tissues, leading to inflammation and tissue damage. The symptoms typically occur 1-2 weeks after exposure to the antigen. Anaphylactic reaction (choice A) is immediate and involves IgE antibodies. Cytotoxic reaction (choice B) involves destruction of cells by antibodies. Delayed hypersensitivity (choice C) usually takes 48-72 hours to develop and involves T-cells. Therefore, the correct answer is D as it aligns with the symptoms and timeline of a type III hypersensitivity reaction.

Correct Answer: C

Rationale: Step 1: S. aureus is known to produce hemolysins, leucocidins, and enterotoxin. Step 2: S. aureus colonies usually exhibit golden-yellow pigmentation with beta-hemolytic zones. Step 3: S. aureus has developed resistance to penicillin due to the production of beta-lactamase. Step 4: Therefore, statement C is not true as S. aureus is not always sensitive to penicillin. Summary: Choices A and B are correct statements about S. aureus, while choice C is incorrect due to the increasing penicillin resistance seen in S. aureus.

Correct Answer: D

Rationale: The correct answer is D: Proteus vulgaris. Non-lactose-fermenting, Gram-negative rods that produce gas in a nutrient broth are characteristic of Proteus species. Proteus vulgaris is known for its swarming motility and ability to produce hydrogen sulfide gas. Salmonella typhi and Shigella dysenteriae are Enterobacteriaceae that do not produce gas in a nutrient broth. Escherichia coli is a lactose-fermenting bacterium and would not be expected to produce gas in a nutrient broth.