A 40-day-old infant product of difficult vaginal delivery, presented with repeated vomiting, pallor, and recurrent seizures. On examination, occipitofrontal circumference was 41 cm. Lab study showed; Hb level, 7 gm/dl. You suspect intracranial hemorrhage. Of the following, the MOST likely site of hemorrhage is

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Question 1 of 5

A 40-day-old infant product of difficult vaginal delivery, presented with repeated vomiting, pallor, and recurrent seizures. On examination, occipitofrontal circumference was 41 cm. Lab study showed; Hb level, 7 gm/dl. You suspect intracranial hemorrhage. Of the following, the MOST likely site of hemorrhage is

Correct Answer: A

Rationale: Subdural hemorrhage (A) fits difficult delivery, late seizures, and anemia at 40 days, more than subarachnoid (B), periventricular (C), IVH (D), or intraparenchymal (E) in term infants.

Question 2 of 5

Unconjugated bilirubin binds to albumin on specific bilirubin binding sites; in a newborn each 1 g of albumin binds to

Correct Answer: C

Rationale: 1 g albumin binds ~8.5 mg bilirubin (C) in newborns, per binding capacity studies.

Question 3 of 5

The incidence of meconium-stained amniotic fluid in term and post-term deliveries is

Correct Answer: B

Rationale: Meconium-stained fluid occurs in ~15% (B) of term/post-term deliveries, per obstetric data.

Question 4 of 5

Early signs of kernicterus are noted after day 4 of life, the earliest clinical manifestations is

Correct Answer: B

Rationale: Lethargy (B) is the earliest kernicterus sign, appearing after day 4, per neurologic progression.

Question 5 of 5

Coagulation factors do not pass through the placenta to the fetus, and newborn infants have relatively low level of factor

Correct Answer: C

Rationale: Newborns have low vitamin K-dependent factors, especially VII (C), per neonatal hemostasis.

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