A 4-year-old boy with asthma has had mild wheezing only four times since you began treating him 6 months ago with theophylline... You should consider the likely cause of vomiting to be

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Question 1 of 5

A 4-year-old boy with asthma has had mild wheezing only four times since you began treating him 6 months ago with theophylline... You should consider the likely cause of vomiting to be

Correct Answer: C

Rationale: Theophylline toxicity is likely due to the interaction with erythromycin/sulfisoxazole, which inhibits theophylline metabolism.

Question 2 of 5

A normal platelet count with prolonged bleeding time is seen in:

Correct Answer: B

Rationale: Von Willebrand disease leads to prolonged bleeding time due to defective platelet adhesion despite a normal platelet count.

Question 3 of 5

The child with polyarticular JIA often has a more prolonged course of active joint inflammation and requires early and aggressive therapy. Of the following, the predictor that carries the WORST prognosis is

Correct Answer: D

Rationale: Nodules indicate more severe disease and carry a worse prognosis.

Question 4 of 5

Regarding sodium homeostasis, what is the volume of distribution of sodium?

Correct Answer: D

Rationale: Sodium is primarily distributed in extracellular fluid, with a volume of distribution of about 0.6 times total body weight, including interstitial and intravascular compartments.

Question 5 of 5

Juvenile localized scleroderma (LS) is generally insidious with skin manifestations that vary according to disease subtype. Up to 25% of children with LS have extracutaneous manifestations including arthritis and neurological symptoms. Of the following, the subtype that is MOST commonly associated with neurological manifestations is

Correct Answer: D

Rationale: En coup de sabre is associated with neurological complications due to its location on the face and scalp.

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