ATI RN
Ricci Maternity and Pediatrics NCLEX Question Immunization Questions
Question 1 of 5
A 4-year-old boy presents with chronic granulomatous disease (CGD), confirmed with a nitro blue tetrazolium (NBT) test. Which of the following pathogens could this child still mount a defense against?
Correct Answer: D
Rationale: CGD impairs oxidative burst; Streptococcus is less reliant on this for clearance.
Question 2 of 5
Potent inducer of apoptosis
Correct Answer: C
Rationale: Fas ligand on cytotoxic T cells binds Fas on target cells, potently inducing apoptosis.
Question 3 of 5
DNA vaccines (tested in mice) use the gene for the immunogenic protein and coat it with what element, which is injected into cells and results in antibody production?
Correct Answer: D
Rationale: DNA vaccines use gold particles to deliver genes into cells, triggering protein expression and antibody production.
Question 4 of 5
A young child presents with cervical adenitis and gingivostomatitis. History reveals recurrent pyogenic infections. Tests are done to determine leukocytosis and the presence of cell adhesion molecules. Which of the following is the most likely?
Correct Answer: C
Rationale: LAD impairs leukocyte adhesion, leading to recurrent pyogenic infections and poor wound healing.
Question 5 of 5
A patient presents with symptoms similar to chronic granulomatous disease (CGD). It is found that there is a problem with generation of NADPH. Which of the following is the most likely?
Correct Answer: B
Rationale: G6PD deficiency impairs NADPH production, mimicking CGD by reducing oxidative burst in phagocytes.