ATI RN
Pediatric Immunization NCLEX Questions Ricci Questions
Question 1 of 5
A 4-month-old female presents with diarrhea and malabsorption, and on initial laboratory testing has a WBC count of 900/mm³. Which of the following is the most likely diagnosis?
Correct Answer: D
Rationale: Severe combined immunodeficiency (SCID) presents with severe lymphopenia (WBC 900) and early infections or failure to thrive, like diarrhea, due to absent T and B cell function.
Question 2 of 5
A 5-month-old infant presented with reluctance to feed, lethargy, abdominal distension, and severe gingivitis. The parents are healthy relatives and give history of non-purulent omphalitis with separation of umbilical stump at the age of 2 months. His peripheral smear showed neutrophil count 24,000/mm3. Of the following, the MOST effective life saving measure is
Correct Answer: C
Rationale: Stem cell transplantation corrects leukocyte adhesion deficiency, addressing the underlying genetic defect for long-term survival.
Question 3 of 5
Which of the following best activate NAïVE CD8 lymphocytes
Correct Answer: A
Rationale: Conventional dendritic cells are the most efficient antigen-presenting cells for activating naïve CD8 T cells via cross-presentation on MHC class I.
Question 4 of 5
CD4 in secondary lymphoid organs that has not been exposed to its antigen yet is called?
Correct Answer: C
Rationale: Naïve mature T helper cells (CD4+) reside in secondary lymphoid organs before antigen exposure, distinguishing them from activated or cytotoxic cells.
Question 5 of 5
which of the following is not in LPS recognition pathway
Correct Answer: D
Rationale: CD46 regulates complement, not LPS recognition, which involves CD14, MD2, and MYD88 in the TLR4 pathway.