A 39-year-old man with recurrent migraine headaches presents to his primary care physician for evaluation and treatment. Physical examination of the head and neck is unremarkable. Treatment with zolmitriptan has begun. This agent acts on which of the following receptors in the brain?

A 39-year-old man with recurrent migraine headaches presents to his primary care physician for evaluation and treatment. Physical examination of the head and neck is unremarkable. Treatment with zolmitriptan has begun. This agent acts on which of the following receptors in the brain?

A 37-year-old female with mild arthritis presents to the clinic for follow-up. She states that she is doing much better because of doubling her dose of ibuprofen. Some days, she even triples her dose throughout the day. The physician warns the patient about peptic ulcers and bleeding from taking too much ibuprofen. She is offered alternatives, but the patient refuses because the ibuprofen works so well. What is the most appropriate therapy for this patient to prevent peptic ulcers?

A 39-year-old man with chronic back pain from a spinal cord injury has a pain medication pump placed in his body. Unfortunately, meperidine was placed in the pump instead of the usual medication—morphine. Which of the following effects is possible as a result of this mistake?

A 31-year-old woman presents to the clinic for follow-up of her abdominal pain. The pain has been occurring for a couple of years but has worsened recently. She is often constipated and then will have periods of diarrhea. Her pain does usually improve after a bowel movement. After multiple negative tests, the diagnosis of constipation-predominant irritable bowel syndrome is made. Which of the following is an appropriate treatment for this patient?

A 48-year-old woman with a history of chronic migraine headaches has failed therapy with conservative measures and ibuprofen. Her primary care physician begins treatment with ergotamine. Important adverse reactions to be aware of include which of the following?