ATI RN
Pharmacology Across the Lifespan ATI Questions
Question 1 of 5
A 39-year-old man with chronic back pain from a spinal cord injury has a pain medication pump placed in his body. Unfortunately, meperidine was placed in the pump instead of the usual medication—morphine. Which of the following effects is possible as a result of this mistake?
Correct Answer: C
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 2 of 5
A 48-year-old woman with a history of chronic migraine headaches has failed therapy with conservative measures and ibuprofen. Her primary care physician begins treatment with ergotamine. Important adverse reactions to be aware of include which of the following?
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
An 18-year-old man is brought to the emergency department by a friend after smoking crack cocaine because he was 'acting funny.' His temperature is 38°C (100.4°F), pulse is 110 beats/minute, and he appears agitated. What is the action of cocaine on sympathetic nerves?
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 4 of 5
A 42-year-old woman who is a chemist is brought to the emergency department because of a 1-hour history of severe abdominal cramps, nausea and vomiting, hypotension, bradycardia, sweating, and difficulty breathing due to bronchospasm and congestion. Exposure to which of the following is most likely?
Correct Answer: C
Rationale: These symptoms (abdominal cramps, nausea, vomiting, hypotension, bradycardia, sweating, bronchospasm) suggest cholinergic toxicity from an organophosphate like isoflurophate (DFP, C), an irreversible cholinesterase inhibitor. As a chemist, she could have been exposeAcrylamide causes neurotoxicity, cyanogen bromide cyanide poisoning (tachycardia, not bradycardia), phentolamine alpha-blockade (hypotension without bronchospasm), and propranolol (E) beta-blockade (bradycardia without cholinergic signs)—none match this full picture.
Question 5 of 5
A patient requires a high dose of a new antihypertensive medication because the new medication has a significant first-pass effect. What does this mean?
Correct Answer: C
Rationale: A significant first-pass effect means the medication is extensively metabolized in the liver after oral administration, reducing its bioavailability. This requires a higher dose to achieve therapeutic levels. Choice misinterprets circulation, refers to renal excretion (not first-pass), and suggests tolerance, which isn’t the same phenomenon.