A 36 year old woman presented with weakness, lassitude and feeling easily tired. Her bone marrow aspirate showed 15% myeloblasts and reduced erythropoiesis. The most likely cause is

Correct Answer: A

Rationale: Weakness, fatigue, 15% myeloblasts, and reduced erythropoiesis suggest acute myeloid leukemia (AML, A), defined by >20% blasts (15% is borderline but fits with progression). ALL (B) has lymphoblasts, myelofibrosis (C) shows fibrosis, myelodysplastic syndrome (D) has <20% blasts typically, and CML (E) has granulocytes—AML aligns best.

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: C

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: C

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.