A 34-year-old woman complains of fever, fatigue, weight loss, arthralgia, and transient patchy alopecia during the last 3 months. Her review of systems is notable for occasional rhinorrhea and cough that responds well to oral decongestant therapy. Her prior surgical history is notable for cesarean section and tubal ligation at age 31 years. A similar constellation of symptoms occurred 6 months ago during treatment for a cardiovascular disease. Antinuclear antibody testing was positive at her last visit 6 months ago and is still positive at the present time. Presently, her hematocrit is 36% and creatinine is 1.2 mg/dL. The most likely etiology of this constellation of symptoms and findings is related to

A 34-year-old woman complains of fever, fatigue, weight loss, arthralgia, and transient patchy alopecia during the last 3 months. Her review of systems is notable for occasional rhinorrhea and cough that responds well to oral decongestant therapy. Her prior surgical history is notable for cesarean section and tubal ligation at age 31 years. A similar constellation of symptoms occurred 6 months ago during treatment for a cardiovascular disease. Antinuclear antibody testing was positive at her last visit 6 months ago and is still positive at the present time. Presently, her hematocrit is 36% and creatinine is 1.2 mg/dL. The most likely etiology of this constellation of symptoms and findings is related to

A 41-year-old woman with acute myelogenous leukemia is undergoing a weekly intravenous infusion of chemotherapeutic agents. Upon completion of each cycle, she develops severe nausea and vomiting. A pharmacologic agent is administered intravenously, which seems to decrease nausea in this patient. This agent might have a mechanism of action at which of the following receptors?

A 47-year-old male presented with a fungal infection 2 weeks ago and was treated appropriately with an antifungal. However, the man returns today because of noticeable enlargement of his breasts. He read on the Internet that the medication he was given can cause gynecomastia. What antifungal was he most likely given?

A 68-year-old man with recurrence of prostate cancer after prostatectomy has been receiving chemotherapy treatments. His last prostate-specific antigen (PSA) was 1.4. The chemotherapy has caused a decrease in production from his bone marrow. His hemoglobin is 9.6 g/dL, hematocrit is 28.1%, and platelet count is 44,000/μL. What medication can be given to stimulate bone marrow production of platelets?

A 54-year-old woman with a history of left-sided breast cancer has been in remission for 5 years following paclitaxel therapy coupled with surgical resection. She has now noticed a new lump in her left breast close to where the original tumor was excised. A biopsy reveals recurring cancer. After talking with her physician, she decided to undergo more chemotherapy. Her physician prescribes a drug, which interferes with microtubules. Which is a chemotherapy drug that disrupts the microtubule assembly?