ATI RN
ATI Pharmacology Practice A Questions
Question 1 of 5
A 34-year-old man with seasonal allergic rhinitis that has been refractory to oral antihistamines is now placed on Singulair, a leukotriene receptor blocker, to see if this will improve symptoms. Important interactions with this medication include which of the following?
Correct Answer: C
Rationale: Singulair (montelukast) interacts with rifampin , a CYP3A4 inducer that reduces montelukast levels, decreasing efficacy. Ampicillin , chloramphenicol , and tetracycline lack significant interactions. Rifampin's effect is key in refractory rhinitis.
Question 2 of 5
The client receives beclomethasone (Beconase) intranasally as treatment for allergic rhinitis. He asks the nurse if this drug is safe because it is a glucocorticoid. What is the best response by the nurse?
Correct Answer: A
Rationale: Beclomethasone, an intranasal corticosteroid, treats allergic rhinitis with minimal systemic absorption, reducing risks like adrenal suppression seen with oral steroids. The response 'Intranasal glucocorticoids produce almost no serious adverse effects' reassures the client accurately, as side effects (e.g., nasal irritation) are mild and rare. Swallowing isn't a significant concern due to low bioavailability. Prolonged use might increase minor risks (e.g., epistaxis), but isn't the primary safety factor. Once-daily use aligns with dosing but doesn't define safety. The nurse's best response (A) addresses the client's fear with evidence-based reassurance, emphasizing the drug's localized action and safety profile.
Question 3 of 5
Which assessment finding, by the nurse, is a priority concern when a client receives pseudoephedrine (Sudafed)?
Correct Answer: C
Rationale: Pseudoephedrine's sympathomimetic action risks dysrhythmias, making an irregular heart rate a priority concern for immediate reporting. Fever , respiratory rate , and dry mouth are less urgent. C aligns with cardiovascular risks, making it the priority.
Question 4 of 5
The nurse is caring for a client receiving isoniazid (INH) for tuberculosis. Which instruction should the nurse include?
Correct Answer: C
Rationale: Isoniazid treats TB but risks hepatotoxicity, causing jaundice (yellowing skin, choice C), a serious sign needing immediate reporting to prevent liver failure. Food is optional'INH can be taken either way. Tyramine relates to MAOIs, not INH. Bedtime isn't specific'dosing is flexible. Reporting jaundice aligns with INH's side effect profile, critical in TB therapy where long-term use is common, making C the essential instruction for early detection and safety.
Question 5 of 5
The pharmacokinetic elimination half-life of the following drugs mirrors their pharmacodynamic duration and intensity of action:
Correct Answer: C
Rationale: Dobutamine's pharmacodynamic effects closely match its short half-life, as it is rapidly metabolized and its action declines quickly.