ATI RN
ATI Pharmacology Online Practice 2023 A Questions
Question 1 of 5
A 34-year-old man is a chronic alcoholic and is in and out of a rehabilitation center on a monthly basis. His physician administers a blocker of aldehyde dehydrogenase. Which of the following effects is most likely to be exhibited by this patient following administration?
Correct Answer: D
Rationale: Disulfiram, an aldehyde dehydrogenase blocker, is used in alcoholism to deter drinking. When alcohol is consumed, acetaldehyde accumulates, causing nausea . Bradycardia isn't typical; tachycardia may occur with acetaldehyde buildup. Elation and euphoria contradict the aversive intent. Urticaria (E) is possible but less common. Nausea, with flushing and vomiting, creates an unpleasant reaction, reinforcing abstinence. This aligns with disulfiram's mechanism, leveraging acetaldehyde toxicity to modify behavior, distinguishing it from other effects.
Question 2 of 5
A client with type 2 diabetes is prescribed insulin glargine (Lantus). Which statement by the client indicates a need for further teaching?
Correct Answer: B
Rationale: Insulin glargine, a long-acting basal insulin, provides steady glucose control without a peak. Mixing it with regular insulin is incorrect'glargine's pH precipitates if combined, altering its action, indicating a teaching need. Same-time injection ensures consistency. Overnight control and no peak align with its 24-hour, flat profile. The misconception about mixing risks erratic glucose levels, critical in type 2 diabetes where stability is key. Further teaching must clarify glargine's unique formulation, preventing administration errors that could lead to hypo- or hyperglycemia, making B the statement requiring correction.
Question 3 of 5
A patient is mowing his lawn on a hot Saturday afternoon. He begins to notice chest pain. What should his first action be?
Correct Answer: B
Rationale: The patient's first action should be to stop mowing and sit or lie down. Chest pain can be a symptom of a heart attack, and it is important for the patient to immediately rest and avoid physical strain. Continuing to mow the lawn could worsen the condition or lead to further complications. Sitting or lying down will help reduce the heart's workload and minimize the exertion on the body. If the chest pain continues or worsens, seeking medical help should be the next course of action.
Question 4 of 5
What is true about food and drug precautions? Select all that apply.
Correct Answer: A
Rationale: A. You must limit certain types of food or concurrent administration of certain types of drugs: Some foods can interact with certain medications, either reducing their effectiveness or causing potentially harmful side effects. Therefore, it may be necessary to limit or avoid specific foods when taking certain medications.
Question 5 of 5
Which of the following antiparkinsonian drugs may cause vasospasm?
Correct Answer: B
Rationale: Bromocriptine, a dopamine D2 agonist used in Parkinson's, has ergot alkaloid properties, which can cause vasospasm by stimulating vascular smooth muscle receptors, occasionally leading to Raynaud's-like symptoms or digital ischemia. Amantadine, an NMDA antagonist, enhances dopamine release but lacks vasoconstrictive effects. Carbidopa inhibits dopa decarboxylase, aiding levodopa delivery without vascular impact. Entacapone, a COMT inhibitor, extends levodopa's duration but doesn't affect vessels. Ropinirole, a non-ergot agonist, avoids vasospasm. Bromocriptine's ergot-derived vasoconstriction, though rare, distinguishes it among antiparkinsonian drugs, requiring caution in patients with vascular risks.