A 32-year-old G2P1001 woman at 36 weeks gestation presents to the emergency room with a high fever. The fever started 2 days ago and has progressively worsened. It has been associated with chills, nausea, vomiting, and full body aches. The resident suggests starting trimethoprim-sulfamethoxazole as part of the empiric coverage of her infection until blood cultures return. What side effect would be a contraindication to starting trimethoprim-sulfamethoxazole in a pregnant woman?

A 32-year-old G2P1001 woman at 36 weeks gestation presents to the emergency room with a high fever. The fever started 2 days ago and has progressively worsened. It has been associated with chills, nausea, vomiting, and full body aches. The resident suggests starting trimethoprim-sulfamethoxazole as part of the empiric coverage of her infection until blood cultures return. What side effect would be a contraindication to starting trimethoprim-sulfamethoxazole in a pregnant woman?

A 46-year-old man with HIV disease presents to clinic because of a change in the appearance of his face over the past couple of months since he started antiviral therapy. His face looks sunken, particularly in the cheeks. His arms also appear to be wasting, whereas his breast tissue seems larger. He is unsure why this occurred. What medication is most likely responsible for this patients’ appearance?

The mechanism of antibacterial action of penicillins includes all the following EXCEPT:

Sulphonamides are inactivated by:

Sulphonamides are used in the following conditions EXCEPT: