A 32 y.o. man is divorced, has an irregular sexual life. He complains of falling out of hair in the region of eyelashes, eyebrows, scalp. Objectively: diffuse alopecia is observed, eyebrow margin is absent, eyelashes are stair-like (Pinkus' sign). What examination should be carried out first of all?

Correct Answer: A

Rationale: The correct answer is A: Wasserman test, IFT. The patient's symptoms of diffuse alopecia and Pinkus' sign are suggestive of secondary syphilis. The Wasserman test and Immunofluorescence Test (IFT) are used to detect antibodies against Treponema pallidum, the bacterium causing syphilis. This would confirm or rule out syphilis as the underlying cause of the patient's symptoms. Choice B (T.pallidum Immobilization Test) is similar to the Wasserman test but less commonly used. Choice C (Detection of the nasal mucous membrane for M.leprae) is irrelevant as leprosy does not present with the described symptoms. Choice D (Consultation of neuropathist) is premature without ruling out syphilis first. Thus, the Wasserman test, IFT should be the initial examination to investigate the likely cause of the patient's symptoms.

Correct Answer: D

Rationale: The correct answer is D because all three choices, Clostridium botulinum, Morbillivirus morbillorum, and Clostridium tetani, can cause infections of the central nervous system (CNS). Clostridium botulinum can lead to botulism, which affects the nervous system. Morbillivirus morbillorum can cause measles, which can lead to viral encephalitis. Clostridium tetani can cause tetanus, which affects the CNS by producing neurotoxins. Therefore, all three choices are pathogens that can cause infections of the CNS.

Correct Answer: D

Rationale: The correct answer is D: Protoplast. Lipopolysaccharides of Gram-negative bacteria consist of three main components: O-specific polysaccharide chain, R-specific polysaccharide chain, and Lipid A. Protoplast is not a component of lipopolysaccharides. O-specific polysaccharide chain is responsible for serotype specificity, R-specific polysaccharide chain varies among strains, and Lipid A is the endotoxin component. Protoplast refers to a bacterial cell devoid of a cell wall, which is not a component of lipopolysaccharides.

Correct Answer: B

Rationale: The correct answer is B: Spirochete. Lyme disease is caused by the bacterium Borrelia burgdorferi, which is a spirochete. Spirochetes are spiral-shaped bacteria that move by rotating like a corkscrew, which is characteristic of Borrelia burgdorferi. A: Spirillum - Spirillum bacteria are helical-shaped but are not the causative agent for Lyme disease. C: Vibrio - Vibrio bacteria are curved or comma-shaped and are not associated with Lyme disease. D: Diplococcus - Diplococcus bacteria are spherical-shaped and typically occur in pairs, not the causative agent for Lyme disease. Therefore, the correct answer is B because Borrelia burgdorferi is a spirochete bacterium that causes Lyme disease.

Correct Answer: C

Rationale: The correct answer is C because transcription is the process in which messenger RNA transcripts are produced from DNA. During transcription, a specific segment of DNA is transcribed into mRNA by RNA polymerase. Choice A is incorrect because translation, not transcription, involves converting mRNA into protein. Choice B is incorrect as it describes DNA replication, not transcription. Choice D is incorrect because it refers to translation, where polypeptides are synthesized from mRNA. Therefore, choice C is the correct answer as it accurately describes the process of transcription.