A 31-year-old woman with HIV disease complains of vulvar itching, burning, and vaginal discharge with rancid odor for 2 months. She presents to the ambulatory care clinic for evaluation. She has had unprotected sexual intercourse with multiple male partners during the past several weeks. The vaginal discharge is yellow-green in color, frothy, and has a pH of 7.0. Vulvovaginal examination reveals vulvar edema and erythema and petechia on the cervix. Wet smear reveals large numbers of mature epithelial cells, white blood cells, and a fusiform protozoan organism. What is the most appropriate treatment for this patient?

A 31-year-old woman with HIV disease complains of vulvar itching, burning, and vaginal discharge with rancid odor for 2 months. She presents to the ambulatory care clinic for evaluation. She has had unprotected sexual intercourse with multiple male partners during the past several weeks. The vaginal discharge is yellow-green in color, frothy, and has a pH of 7.0. Vulvovaginal examination reveals vulvar edema and erythema and petechia on the cervix. Wet smear reveals large numbers of mature epithelial cells, white blood cells, and a fusiform protozoan organism. What is the most appropriate treatment for this patient?

A 41-year-old man with a history of gastroesophageal reflux disorder and diabetes mellitus is managed with cimetidine and diet/exercise for these disorders. The fact that he takes cimetidine means that the treating physician must be attune to increased effects of which of the following drugs?

A 41-year-old woman with acute myelogenous leukemia is undergoing a weekly intravenous infusion of chemotherapeutic agents. Upon completion of each cycle, she develops severe nausea and vomiting. A pharmacologic agent is administered intravenously, which seems to decrease nausea in this patient. This agent might have a mechanism of action at which of the following receptors?

A 47-year-old male presented with a fungal infection 2 weeks ago and was treated appropriately with an antifungal. However, the man returns today because of noticeable enlargement of his breasts. He read on the Internet that the medication he was given can cause gynecomastia. What antifungal was he most likely given?

A 68-year-old man with recurrence of prostate cancer after prostatectomy has been receiving chemotherapy treatments. His last prostate-specific antigen (PSA) was 1.4. The chemotherapy has caused a decrease in production from his bone marrow. His hemoglobin is 9.6 g/dL, hematocrit is 28.1%, and platelet count is 44,000/μL. What medication can be given to stimulate bone marrow production of platelets?