A 3.2-kg, 40-week's-gestational age male is born by spontaneous vaginal delivery to a 20-year-old white female. Past maternal medical problems reveal a history of easy bruising that required splenectomy at 18 years of age. Current coagulation studies of the mother include a prothrombin time of 12 seconds, a partial thromboplastin time of 25 seconds, fibrinogen of 300 mg/dL, and a platelet count of 175,000. At 3 hours of age, the infant is noted to have multiple petechiae and a platelet count of 15,000. The most likely diagnosis is

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Question 1 of 5

A 3.2-kg, 40-week's-gestational age male is born by spontaneous vaginal delivery to a 20-year-old white female. Past maternal medical problems reveal a history of easy bruising that required splenectomy at 18 years of age. Current coagulation studies of the mother include a prothrombin time of 12 seconds, a partial thromboplastin time of 25 seconds, fibrinogen of 300 mg/dL, and a platelet count of 175,000. At 3 hours of age, the infant is noted to have multiple petechiae and a platelet count of 15,000. The most likely diagnosis is

Correct Answer: C

Rationale: Maternal ITP (C) with splenectomy history can cause neonatal thrombocytopenia via passive antibody transfer.

Question 2 of 5

Matching: Regional lymphadenopathy - Rubella

Correct Answer: B

Rationale: Rubella (B) typically causes occipital lymphadenopathy.

Question 3 of 5

Which of the following can lead to a possible diagnosis of human immunodeficiency virus (HIV) in a child? (Select one that does not apply.)

Correct Answer: D

Rationale: Children with HIV commonly exhibit frequent respiratory infections, intermittent diarrhea, and poor weight gain due to underlying cellular immunodeficiency.

Question 4 of 5

A child with hemophilia A fell and injured a knee while playing outside. The knee is swollen and painful. Which of the following measures should be taken to stop the bleeding? (Select one that does not apply.)

Correct Answer: C

Rationale: Immobilization and elevation help induce vasoconstriction and reduce bleeding. Factor VIII administration replaces the deficient clotting factor in hemophilia A.

Question 5 of 5

A nurse is caring for a 5-year-old with sickle cell vaso-occlusive crisis. Which of the following orders should the nurse question?

Correct Answer: D

Rationale: Demerol (meperidine) is generally avoided in sickle cell crisis because of its seizure risk. Oral fluids should not be restricted; hydration is critical to prevent further vaso-occlusion.

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