ATI RN
ATI VATI Pharmacology Assessment Questions
Question 1 of 5
A 27-year-old man with recurrent asthma attacks is being considered for preventative therapy with cromolyn sodium. This agent is not effective as an acute treatment of an asthma attack because of the lack of which of the following properties?
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 2 of 5
Which one of the following statements about lithium is accurate?
Correct Answer: C
Rationale: Lithium, used for bipolar disorder, stabilizes mood via inositol depletion and other mechanisms. It can cause hypothyroidism, not hyperthyroidism, by inhibiting thyroid hormone release. High sodium intake increases lithium excretion, lowering plasma levels, not raising them. Common adverse effects include acne (sebaceous gland stimulation), polydipsia, and polyuria (due to nephrogenic diabetes insipidus from ADH antagonism), affecting many patients and requiring monitoring. Teratogenicity concerns focus on Ebstein's anomaly (cardiac defect), not spina bifida, though risks are low with modern management. Sedation isn't rapid; therapeutic effects take days to weeks. The constellation of acne, polydipsia, and polyuria reflects lithium's broad physiological impact, making it the most accurate description of its side effect profile.
Question 3 of 5
A patient has taken two doses of interferon Alfa-2b (Intron-A). He comes to the clinic today with the following complaints. Which symptoms would the nurse identify as common adverse effects of this therapy?
Correct Answer: A
Rationale: Interferon Alfa-2b is an immunomodulatory drug used for conditions like hepatitis or cancer, known for causing flu-like symptoms and systemic effects. Common adverse effects include dizziness, fatigue, and anorexia (loss of appetite), as listed in the correct answer (1, 3, 4). Dizziness reflects the drug's impact on the central nervous system, often reported early in therapy. Loss of appetite and fatigue are also hallmark symptoms due to interferon's influence on metabolism and energy levels. An itchy rash , while possible as a hypersensitivity reaction, is less commonly associated with interferon compared to these systemic effects. The nurse must recognize these as expected side effects, distinguishing them from severe reactions requiring intervention. Since the question asks for common adverse effects and the correct answer includes multiple symptoms, choice A (dizziness) is a key identifier among them, supported by its prevalence in clinical use, making it the primary focus here.
Question 4 of 5
Discharge planning for the client prescribed tetracycline will include which instruction?
Correct Answer: C
Rationale: Tetracycline, a broad-spectrum antibiotic, requires specific administration instructions to ensure efficacy. It binds to divalent cations like calcium (in milk), magnesium (in antacids), and iron (in supplements), forming insoluble chelates that reduce absorption, rendering it ineffective. The instruction 'Do not take the medication with milk' is critical to avoid this interaction, ensuring therapeutic levels are achieved. Taking it with antacids or iron similarly impairs absorption, making these incorrect and potentially harmful suggestions. Decreasing vitamins is irrelevant, as vitamins don't typically interfere unless combined with minerals. This guidance aligns with tetracycline's pharmacokinetics, emphasizing timing away from meals or supplements containing these ions. Effective discharge teaching prevents treatment failure, especially for infections requiring consistent drug levels, making C the priority instruction for the client's understanding and adherence.
Question 5 of 5
A patient says, 'I have such bad seasonal allergies. Is there anything I can take to keep them from happening?' What information should the nurse provide?
Correct Answer: C
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.