ATI RN
ABVD chemotherapy drugs Questions
Question 1 of 5
A 27-year-old man presented to the clinic for routine abroad trip preparation. He is traveling to the Caribbean in 1 month. Antidiarrheals and antimalarials are prescribed. It is noted that the patient has a history of epilepsy, latent TB, and has contracted malaria once on a prior trip. His vaccines are up to date, and he has no allergies. What medication is contraindicated for this patient?
Correct Answer: D
Rationale: Mefloquine is contraindicated in epilepsy due to its risk of neuropsychiatric side effects, including seizures, which could exacerbate his condition.
Question 2 of 5
A 22-year-old woman with HIV disease notes progressive visual disturbance noted by a decrease in visual acuity. She presents to the ambulatory care clinic for further evaluation and treatment. Funduscopic examination reveals large white areas proximal to the macula with perivascular exudates and hemorrhages. Treatment of this condition involves which of the following agents?
Correct Answer: B
Rationale: Oral ganciclovir (or valganciclovir) treats CMV retinitis in HIV patients, characterized by retinal white areas and hemorrhages, by inhibiting viral DNA polymerase.
Question 3 of 5
A 35-year-old African American male in the military is hospitalized with an MRSA skin infection. The patient starts treatment with an antibiotic and becomes anemic and jaundiced. On peripheral blood smear, Heinz bodies are seen within red blood cells. What is the mechanism of action of the antibiotic given to this patient?
Correct Answer: D
Rationale: The antibiotic is likely dapsone (used for MRSA in some cases), which inhibits folic acid metabolism and causes oxidative stress in G6PD-deficient patients, leading to hemolysis, Heinz bodies, anemia, and jaundice.
Question 4 of 5
A 35-year-old male with ulcerative colitis has recently been diagnosed with colon cancer. He needs to have a partial colectomy to remove the distal portion of the colon. The patient has no other medical problems. What antibiotic is most appropriate prior to his upcoming colectomy?
Correct Answer: D
Rationale: Neomycin, an oral aminoglycoside, is used for bowel preparation before colectomy to reduce gut flora, minimizing postoperative infection risk.
Question 5 of 5
A 26-year-old sexually active HIV-negative man presents to his primary care physician with a nonpruritic maculopapular rash on his palms. He reports that about 6 weeks ago, he developed a nonpainful ulcer on his penis that healed spontaneously. He is injected with a single dose of benzathine penicillin G intramuscularly and sent home. What, if anything, should have been done differently for this patient’s care?
Correct Answer: C
Rationale: A single IM dose of benzathine penicillin G is the standard treatment for early syphilis (primary or secondary), as seen with his chancre and rash, requiring no additional action.