A 25-year-old patient was delivered to an infectious diseases unit on the 3rd day of illness with complaints of headache, pain in lumbar spine and gastrocnemius muscles, high fever, chill. Objectively: condition of moderate severity. Scleras are icteric. Pharynx is hyperemic. Tongue is dry with dry brown coating. Abdomen is distended. Liver is enlarged by 2 cm. Spleen is not enlarged. Palpation of muscles, especially gastrocnemius muscles, is painful. Urine is dark in color. Stool is normal in color. The most likely diagnosis is:

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Microbiology Chapter 13 Test Bank Questions

Question 1 of 5

A 25-year-old patient was delivered to an infectious diseases unit on the 3rd day of illness with complaints of headache, pain in lumbar spine and gastrocnemius muscles, high fever, chill. Objectively: condition of moderate severity. Scleras are icteric. Pharynx is hyperemic. Tongue is dry with dry brown coating. Abdomen is distended. Liver is enlarged by 2 cm. Spleen is not enlarged. Palpation of muscles, especially gastrocnemius muscles, is painful. Urine is dark in color. Stool is normal in color. The most likely diagnosis is:

Correct Answer: A

Rationale: The correct diagnosis is Leptospirosis. Leptospirosis presents with headache, fever, muscle pain, jaundice, and kidney involvement. The patient's symptoms of headache, lumbar and muscle pain, high fever, icteric scleras, and dark urine are classic for Leptospirosis. The enlarged liver could be due to liver involvement in the disease. The absence of splenic enlargement and normal stool color rule out malaria. Infectious mononucleosis typically presents with sore throat and lymphadenopathy, which are absent in this case. Viral hepatitis A may present with similar symptoms, but the presence of muscle pain and dark urine is more indicative of Leptospirosis. Therefore, based on the patient's symptoms and clinical findings, Leptospirosis is the most likely diagnosis.

Question 2 of 5

As an example of specific human parasites one can name Plasmodium falciparum, human pinworm and some others. The source of parasite invasion is always a human. Such specific human parasites cause the diseases that are called:

Correct Answer: A

Rationale: The correct answer is A: Anthroponoses. This term refers to diseases caused by specific human parasites that are transmitted directly from human to human. In this case, the source of parasite invasion is always a human host. This term specifically describes diseases caused by parasites that exclusively infect humans. Choice B: Zoonoses refers to diseases that can be transmitted from animals to humans. Choice C: Anthropozoonoses is a combination of zoonoses and anthroponoses, which is not applicable in this scenario. Choice D: Infections is a general term that does not specify the source or type of parasite causing the disease.

Question 3 of 5

A woman delivered a dead child with multiple developmental defects. What protozoan disease might have caused the intrauterine death?

Correct Answer: A

Rationale: The correct answer is A: Toxoplasmosis. Toxoplasmosis is a parasitic infection caused by Toxoplasma gondii, which can be transmitted from mother to fetus during pregnancy, leading to congenital toxoplasmosis. This infection can result in stillbirth, multiple developmental defects, and intrauterine death. Leishmaniasis (B), Malaria (C), and Amebiasis (D) are caused by different parasites and do not typically lead to intrauterine death or developmental defects in the fetus.

Question 4 of 5

From a medicinal herb a certain phytopathogenic microorganism was secured. In the nutrient medium it forms "fried egg"colonies. What is the most likely agent?

Correct Answer: C

Rationale: Step 1: "Fried egg" colonies typically refer to colonies with a raised center and flattened periphery, resembling the appearance of a fried egg. Step 2: Actinomycetes are filamentous bacteria known to form "fried egg" colonies in nutrient medium. Step 3: Actinomycetes are commonly found in soil and are known to be phytopathogenic microorganisms. Step 4: Actinomycetes produce secondary metabolites with medicinal properties, making them a likely agent from a medicinal herb. Overall, the correct answer is C (Actinomycetes) as they fit the description provided in the question and are commonly associated with the given scenario. The other choices are incorrect as they do not exhibit the specific characteristics mentioned in the question or are not typically associated with forming "fried egg" colonies in nutrient medium.

Question 5 of 5

A male patient has been diagnosed with gastric ulcer. Bacteriological examination of biopsy material from the affected part of stomach revealed small colonies of gram-negative, oxide reductase-positive flexibacteria that grew on the chocolate agar on the fifth day. Which of the following microorganisms is the most likely causative agent?

Correct Answer: A

Rationale: The correct answer is A: Helicobacter pylori. This bacterium is the most likely causative agent of gastric ulcers. Here's the rationale: 1. Helicobacter pylori is commonly associated with gastric ulcers. 2. It is a gram-negative bacterium that grows on chocolate agar and is oxide reductase-positive. 3. The slow growth on the fifth day is characteristic of H. pylori. 4. Campylobacter jejuni and Campylobacter fetus are not typically associated with gastric ulcers. 5. Mycoplasma hominis is a bacterium that lacks a cell wall and is not commonly found in gastric ulcers.

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