ATI RN
Chemotherapy drugs Questions
Question 1 of 5
A 24-year-old sexually active woman presents with vaginal itching and a greenish, frothy vaginal discharge. Her boyfriend is asymptomatic. She is prescribed with metronidazole for Trichomonas infection. Which of the following is involved in metronidazole’s action?
Correct Answer: B
Rationale: Metronidazole disrupts DNA in anaerobic organisms like Trichomonas vaginalis by forming reactive intermediates, leading to cell death.
Question 2 of 5
The following precautions about tetracycline use are true EXCEPT:
Correct Answer: D
Rationale: Tetracyclines are contraindicated in pregnancy and early childhood due to effects on teeth and bones, making D the incorrect precaution.
Question 3 of 5
The long-acting penicillin applied for chemoprophylaxis of rheumatic fever as a monthly injection is:
Correct Answer: D
Rationale: Benzathine penicillin is used as a monthly injection for rheumatic fever prophylaxis due to its long-acting depot formulation.
Question 4 of 5
Precautions to reduce crystalluria during sulphonamides use is:
Correct Answer: C
Rationale: Alkalinization of urine enhances sulphonamide solubility, preventing crystal formation in the urinary tract.
Question 5 of 5
The most serious side effect of sulphonamides in neonates is:
Correct Answer: A
Rationale: Sulphonamides displace bilirubin from albumin in neonates, leading to kernicterus, a severe neurological condition.