A 23-year-old woman with lifelong epilepsy controlled with medication has just found out that she is pregnant. She has seizures once a month but seem to be controlled at present. Which of the following statements about epilepsy in pregnancy is true?

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Lifespan Pharmacology Questions

Question 1 of 5

A 23-year-old woman with lifelong epilepsy controlled with medication has just found out that she is pregnant. She has seizures once a month but seem to be controlled at present. Which of the following statements about epilepsy in pregnancy is true?

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 2 of 5

A 54-year-old man with hypertension, alcoholic cirrhosis, and HIV disease is hospitalized for abdominal pain, fatigue, and weakness. His ascites and edema are markedly worse. Physical examination reveals a palpable abdominal fluid wave. Which of the following treatments may be beneficial for this patient?

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 3 of 5

A 27-year-old man was prescribed with an antidepressant for his insomnia. He now presents to the emergency department with priapism of 3 h duration. Which antidepressant was he likely taking?

Correct Answer: D

Rationale: is commonly prescribed off-label for insomnia due to its sedative effects and is notoriously associated with priapism, a prolonged and painful erection, due to its α-adrenergic blockade and serotonergic properties. Bupropion has a low incidence of sexual side effects and is stimulating, not sedating. Duloxetine (an SNRI) and sertraline (an SSRI) can cause sexual dysfunction but rarely priapism. Imipramine, a tricyclic antidepressant, has anticholinergic effects but is less linked to priapism than trazodone.

Question 4 of 5

A 21-year-old woman comes to the physician for counseling prior to conception. She delivered a female newborn with anencephaly 1 year ago. The newborn died at the age of 4 days. She asks the physician if she can take any vitamins to decrease her risk for conceiving a fetus with anencephaly. It is most appropriate for the physician to recommend which of the following vitamins?

Correct Answer: B

Rationale: Folic acid supplementation (0.4-4 mg daily) reduces the risk of neural tube defects (NTDs) like anencephaly, which results from failure of neural tube closure. Her prior NTD-affected pregnancy increases recurrence risk, making folic acid critical preconception. Biotin (A), thiamine (C), riboflavin (D), pyridoxine (E), and B₁₂ (F) don’t prevent NTDs; B₁₂ deficiency causes other defects, not anencephaly.

Question 5 of 5

The nurse is monitoring a patient taking furosemide for heart failure. Which electrolyte imbalance must the nurse be alert for?

Correct Answer: C

Rationale: Furosemide, a loop diuretic, increases potassium excretion in the loop of Henle, commonly causing hypokalemia in heart failure patients. This can lead to arrhythmias, a critical concern. Hyperkalemia occurs with potassium-sparing diuretics, hypernatremia is rare with furosemide, and hyponatremia is less common than hypokalemia.

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