ATI RN
Basic Principles of Pharmacology Quizlet Questions
Question 1 of 5
A 22-year-old woman suffering from asthma was prescribed albuterol by inhalation. Albuterol is a bronchodilating drug with a molecular weight of 239 daltons. Which of the following permeation processes most likely accounted for the transfer of the drug through the bronchial mucosa?
Correct Answer: C
Rationale: Facilitated diffusion is the most likely permeation process for the transfer of albuterol through the bronchial mucosa. This process involves the use of carrier proteins to facilitate the movement of molecules across the membrane. Since albuterol is a relatively small molecule with a molecular weight of 239 daltons, it is more likely to utilize facilitated diffusion rather than bulk flow transport, endocytosis, or active transport. Lipid diffusion is not as efficient for larger molecules like albuterol, making facilitated diffusion the most suitable choice for this scenario.
Question 2 of 5
What percentage of atenolol bound if a dose of 50 mg/d had been administered?
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
What percentage of the administered drug will be eliminated by the liver?
Correct Answer: C
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 4 of 5
Which of the following drugs has the largest volume of distribution?
Correct Answer: C
Rationale: The volume of distribution (Vd) is a pharmacokinetic parameter that indicates the extent of a drug's distribution in the body. The drug with the largest Vd will have the most extensive distribution. In this case, Drug R has the largest Vd of 100 L, indicating that it has the largest volume of distribution among the options provided.
Question 5 of 5
Which of the curves best depicts the log dose-response curve of that agonist when a xed dose of a competitive α antagonist is given concomitantly?
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.