ATI RN
ATI Pharmacology Practice B Questions
Question 1 of 5
A 22-year-old woman is interested in taking oral contraceptives for the prevention of pregnancy. The most likely benefit in terms of disease prevention from oral contraceptives is which of the following?
Correct Answer: B
Rationale: Oral contraceptives (OCs) reduce ectopic pregnancy risk , by preventing ovulation. Colon cancer , breast cancer , thyroid cancer , and teratoma (E) aren't consistently linked. Ectopic risk drops with suppressed ovulation, a well-established OC benefit.
Question 2 of 5
Oral decongestants differ from intranasal decongestants in that oral decongestants
Correct Answer: B
Rationale: Oral decongestants (e.g., pseudoephedrine) act systemically, vasoconstricting vessels beyond the nose, causing effects like hypertension , unlike intranasal decongestants (e.g., oxymetazoline), which are localized but risk rebound congestion. Oral efficacy isn't inherently superior; it's slower. Rebound is nasal-specific. High efficacy is vague. Choice B highlights systemic impact, a key distinction nurses must recognize for safe administration.
Question 3 of 5
What is the maximal response a drug can produce?
Correct Answer: C
Rationale: Efficacy refers to the maximal response a drug can produce, regardless of the dose. It is a measure of how well a drug can produce its desired effect. Potency, on the other hand, refers to the amount of drug required to produce a specific effect and is not related to the maximal response. An agonist is a drug that binds to and activates a receptor. Bioavailability is the fraction of the administered dose of a drug that reaches the systemic circulation.
Question 4 of 5
A 53-year-old man with chronic neuropathic back pain and depression is managed with amitriptyline. He has recently complained of urinary frequency and was given a prescription for Ditropan. He now complains of acute abdominal pain and is unable to pass flatus or bowel movement. What is the most likely explanation of this finding?
Correct Answer: C
Rationale: Amitriptyline and Ditropan (oxybutynin), both anticholinergics, risk paralytic ileus , stopping GI motility, causing pain and obstruction. Hepatitis , pancreatitis , overdose , and normalcy (E) don't fit. Combined anticholinergic effects explain this acute issue.
Question 5 of 5
The nurse reviews the patient’s medication history. Based on the patient’s prolonged use of topical corticosteroids, which assessment will the nurse include? (Select all that apply.)
Correct Answer: B
Rationale: Prolonged use of topical corticosteroids can cause thinning of the skin (B) and purpura (D) due to decreased collagen production and increased fragility of blood vessels. Weight gain (A) is associated with systemic, not topical, corticosteroid use. Erythematous lesions (C) are not typically caused by topical corticosteroids.