ATI RN
Pediatric Infectious Diseases Questions
Question 1 of 5
A 2-year- old girl presented with abdominal mass, periorbital ecchymoses and ataxia. Of the following, the MOST likely diagnosis is
Correct Answer: B
Rationale: Neuroblastoma fits with abdominal mass, periorbital ecchymoses (raccoon eyes), and ataxia (possible opsoclonus-myoclonus).
Question 2 of 5
Neo-adjuvant chemotherapy means
Correct Answer: C
Rationale: Neo-adjuvant chemotherapy is given before surgery to shrink the tumor while it remains in place.
Question 3 of 5
Which of the following genotypes can predispose a child to the development of acute leukemia?
Correct Answer: C
Rationale: Bloom syndrome, a DNA repair disorder, increases the risk of leukemia due to genomic instability.
Question 4 of 5
The commonest translocation in infantile acute lymphoblastic leukemia is
Correct Answer: C
Rationale: t(4;11) (MLL rearrangement) is the most frequent translocation in infantile ALL, linked to poor prognosis.
Question 5 of 5
A boy with acute lymphoblastic leukemia is assigned to be of very high risk group if he had got which of the following features?
Correct Answer: D
Rationale: t(9;22) (Philadelphia chromosome) confers a very high risk in ALL due to poor prognosis.