A 2-year-old child presented with fever, irritability, and inability to walk; on examination there is erythema, swelling, warmth, and tenderness over the lower thigh; radiographs of the left knee showed focal destruction of the distal femoral metaphysis and periosteal reaction. Of the following, the MOST common etiological pathogen of this condition is

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Pediatric Infectious Disease Questions

Question 1 of 5

A 2-year-old child presented with fever, irritability, and inability to walk; on examination there is erythema, swelling, warmth, and tenderness over the lower thigh; radiographs of the left knee showed focal destruction of the distal femoral metaphysis and periosteal reaction. Of the following, the MOST common etiological pathogen of this condition is

Correct Answer: B

Rationale: S. aureus (B) is the most common cause of osteomyelitis in children, per pediatric orthopedics.

Question 2 of 5

Leukocoria is a manifestation of

Correct Answer: B

Rationale: Leukocoria (white pupil) is a classic sign of retinoblastoma.

Question 3 of 5

A 3-year- old girl with newly diagnosed paravertebral neuroblastoma, presented to the pediatric emergency department with rapid onset weakness of both lower limbs following a 3-day history of severe back pain. Of the following, the MOST possible diagnosis is

Correct Answer: C

Rationale: Spinal cord compression from a paravertebral neuroblastoma explains the lower limb weakness and back pain.

Question 4 of 5

Almost all the following pediatric malignancies require chemotherapy EXCEPT

Correct Answer: B

Rationale: Low-grade neuroblastoma may be managed with observation or surgery alone in some cases, unlike the others requiring chemotherapy.

Question 5 of 5

A translocation between chromosomes 9 and 22 (BCR-ABL) plays an important role in the development of

Correct Answer: B

Rationale: The BCR-ABL translocation (Philadelphia chromosome) is a hallmark of chronic myeloid leukemia.

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