ATI RN
Pediatric Immunization Test Questions Questions
Question 1 of 5
A 2-year-old boy presented with failure to thrive, neonatal hypocalcemic seizure, and three attacks of sepsis. Examination reveals cleft palate and holo-systolic murmur. Of the following, the genetic predisposition of this condition is
Correct Answer: A
Rationale: These features (hypocalcemia, heart defect, cleft palate) are classic for DiGeorge syndrome, caused by 22q11.2 microdeletion.
Question 2 of 5
A 13-month-old girl presented with failure to thrive, repeated chest infection, and fatty offensive diarrhea. Hemoglobin level 8.8 gm/dl, platelate count 150/mm3, white blood cell count 3.500/mm3, with absolute neutrophil count (ANC) 500/μL. Of the following, the MOST likely diagnosis is
Correct Answer: D
Rationale: Shwachman-Diamond syndrome features neutropenia, pancreatic insufficiency (fatty diarrhea), and failure to thrive, matching this presentation.
Question 3 of 5
In chronic granulomatous disease (CGD), the best method to detect and follow up deep-seated infection is
Correct Answer: D
Rationale: C-reactive protein is a sensitive marker for inflammation and infection, useful for monitoring deep-seated infections in CGD.
Question 4 of 5
Which of the following is a large genomic region or gene family found in most vertebrates, playing an important role in immunity?
Correct Answer: B
Rationale: MHCs are a large gene family in vertebrates critical for presenting antigens to T cells, distinguishing them from HLAs (a subset of MHC in humans) and other options.
Question 5 of 5
Which of the following components of the innate immune system involves the release of histamine?
Correct Answer: D
Rationale: Tissue mast cells release histamine during innate responses, such as allergies or inflammation, unlike the other listed cells.