ATI RN
Microbiology An Introduction Test Bank Questions
Question 1 of 5
A 19 year old woman suffers from primary syphilis. Doctor administered her complex therapy that includes benzylpenicillin sodium salt. What is the mechanism of action of this drug?
Correct Answer: A
Rationale: The correct answer is A. Benzylpenicillin sodium salt, also known as penicillin G, works by blocking the synthesis of peptidoglycan in the microbial cell wall. Peptidoglycan is crucial for the structural integrity of bacterial cell walls. By inhibiting its synthesis, penicillin disrupts the cell wall formation, leading to cell lysis and bacterial death. Choices B, C, and D are incorrect because penicillin does not target cytoplasm proteins, thiol enzymes, or RNA synthesis. Penicillin's primary mode of action is specifically related to interfering with bacterial cell wall synthesis.
Question 2 of 5
A patient has symptoms of inflammation of urogenital tracts. Examination of a vaginal smear revealed big monocellular, pear-shaped organisms with the pointed spike at the posterior end of body, big nucleus and undulating membrane. What protozoa were found in the smear?
Correct Answer: A
Rationale: Rationale: The correct answer is A: Trichomonas vaginalis. 1. Symptoms of urogenital inflammation match Trichomonas vaginalis infection. 2. Description matches Trichomonas vaginalis characteristics: pear-shaped, pointed spike, big nucleus, undulating membrane. 3. Trichomonas hominis and buccalis do not typically infect urogenital tracts. 4. Trypanosoma gambiense causes African trypanosomiasis, not urogenital infections.
Question 3 of 5
UN volunteers have arrived in Nigeria to assist the locals in aftermath of earthquakes. What drug should they prescribe for individual chemoprophylaxis of malaria?
Correct Answer: D
Rationale: The correct answer is D: Primaquine. Primaquine is used for individual chemoprophylaxis of malaria caused by Plasmodium vivax and Plasmodium ovale. It is effective in preventing the relapse of these malaria species by eliminating the liver forms of the parasites. Chingamin (A) is not a commonly used drug for malaria prophylaxis. Pyrantel (B) is an anthelmintic drug used for treating parasitic worm infections, not malaria. Pyrimethamine (Chloridinum) (C) is primarily used in combination with sulfadoxine for treating uncomplicated malaria, not for chemoprophylaxis.
Question 4 of 5
A 28 y.o. homeless male was admitted to the hospital because of initial diagnosis "influenza". Roseolo-petechiae rash has appeared on the trunk and internal surfaces of the limbs on the fifth day. Temperature is 410C, euphoria, face and sclera's hyperemia, tongue tremor, tachycardia, splenomegaly, excitement. What is the most probable diagnosis?
Correct Answer: C
Rationale: The most probable diagnosis for the homeless male with symptoms of roseolo-petechiae rash, hyperemia, tachycardia, splenomegaly, and euphoria is Leptospirosis. Leptospirosis is a bacterial infection commonly associated with exposure to contaminated water or soil, which is prevalent in homeless populations. The initial diagnosis of "influenza" fits with the flu-like symptoms. The appearance of roseolo-petechiae rash and other symptoms like hyperemia, tachycardia, splenomegaly, and euphoria are consistent with leptospirosis. The other choices can be ruled out: A) Typhus typically presents with headache, fever, and rash, but not the specific symptoms described. B) Alcoholic delirium is more likely with a history of alcohol abuse and presents with confusion, disorientation, and hallucinations. D) Abdominal typhoid presents with prolonged fever, abdominal pain
Question 5 of 5
During bacteriological examination of the purulent discharge obtained from a postoperative wound an inoculation on meat infusion agar has been performed. The inoculation has resulted in large colorless mucous colonies that in 24 hours with exposure to sunlight developed green-blue pigmentation and smell of honey or jasmine. Bacterioscopy revealed gram-negative lophotrichea. What bacterial culture is contained in purulent discharge?
Correct Answer: A
Rationale: The correct answer is A: Pseudomonas aeruginosa. Pseudomonas aeruginosa is a gram-negative bacterium known for its green-blue pigmentation and sweet, fruity odor. The large colorless mucous colonies that develop green-blue pigmentation and honey or jasmine smell point towards Pseudomonas aeruginosa. The bacterioscopy revealing gram-negative lophotrichea further supports this identification. Proteus vulgaris and Klebsiella osaenae do not typically exhibit the described characteristics. Streptomyces griseus is a soil bacterium known for its antibiotic production and is not commonly associated with wound infections.