ATI RN
ATI Pharmacology Online Practice 2023 A Questions
Question 1 of 5
A 19-year-old G1P0 woman at 34 weeks gestation lost her eyeglasses for a day. Constant squinting causes her to develop a headache. She asks her doctor for a pain reliever. Which of the following drugs may disrupt her fetus' circulatory system?
Correct Answer: D
Rationale: Pain relief in pregnancy avoids fetal harm. Ketorolac , an NSAID, risks ductal closure, disrupting fetal circulation. Acetaminophen , Codeine , Hydrocodone , and Morphine (E) are safer. Ketorolac's prostaglandin inhibition contraindicates it late in gestation.
Question 2 of 5
A 34-year-old man is a chronic alcoholic and is in and out of a rehabilitation center on a monthly basis. His physician administers a blocker of aldehyde dehydrogenase. Which of the following effects is most likely to be exhibited by this patient following administration?
Correct Answer: D
Rationale: Disulfiram, an aldehyde dehydrogenase blocker, is used in alcoholism to deter drinking. When alcohol is consumed, acetaldehyde accumulates, causing nausea . Bradycardia isn't typical; tachycardia may occur with acetaldehyde buildup. Elation and euphoria contradict the aversive intent. Urticaria (E) is possible but less common. Nausea, with flushing and vomiting, creates an unpleasant reaction, reinforcing abstinence. This aligns with disulfiram's mechanism, leveraging acetaldehyde toxicity to modify behavior, distinguishing it from other effects.
Question 3 of 5
The following drugs can induce malignant hyperthermia:
Correct Answer: B
Rationale: Succinylcholine is a trigger for malignant hyperthermia in susceptible individuals due to its effects on calcium release in muscle cells.
Question 4 of 5
Restoration of blood flow results through the dissolution of clot by:
Correct Answer: B
Rationale: Plasmin is an enzyme that is responsible for breaking down fibrin, a protein that forms blood clots. When an area of vessel needs to have its blood flow restored, such as after a clot has formed, plasmin is activated to dissolve the clot. By breaking down the fibrin mesh of the clot, plasmin helps restore normal blood flow in the affected vessel. Therefore, the restoration of blood flow results through the dissolution of clot by plasmin, making option B the correct answer.
Question 5 of 5
Gold sodium thiomalate is prescribed to a client with rheumatoid arthritis. Which of the following side effects indicates an overdose of the medication?
Correct Answer: D
Rationale: A metallic taste is a common sign of gold salt toxicity, indicating an overdose. Flushing, dizziness, and joint pain are side effects but are not specific to overdose. Gold sodium thiomalate requires careful monitoring to prevent toxicity, and any signs of overdose should be reported immediately.