ATI RN
Pediatric Immunization Practice Questions Questions
Question 1 of 5
A 17-month-old girl presented with history of recurrent attacks of pneumonia since the age of 8 months. You suspect a predominant B-cell defect. Of the following, the BEST simple initial screening test is
Correct Answer: D
Rationale: Isohemagglutinins titer is a functional test for B-cell activity, measuring naturally occurring antibodies (anti-A/anti-B), making it an effective initial screen for B-cell defects.
Question 2 of 5
A 4-year-old boy presented with high fever, decreased appetite, aphthous stomatitis, and cellulitis of the right calf muscle. His absolute neutrophil count (ANC) was 600/μL. The MOST likely organisms causing this condition are
Correct Answer: D
Rationale: Neutropenia predisposes to bacterial infections; Staphylococcus aureus and gram-negative bacteria (e.g., Pseudomonas) are common culprits in cellulitis and stomatitis.
Question 3 of 5
In patient with Chédiak-Higashi syndrome, the only curative therapy is hematopoietic stem cell transplantation which correct all the following EXCEPT
Correct Answer: A
Rationale: HSCT corrects immune and hematologic defects in Chédiak-Higashi but not progressive neuropathy, which is neurologic in origin.
Question 4 of 5
The immune system uses as well as molecules (e.g. complement components). The immune system uses as well as antigen recognition molecules.
Correct Answer: B
Rationale: The immune system has two main branches: innate and adaptive. Innate immunity uses phagocytes (e.g., macrophages) as cells and complement components as molecules, while adaptive immunity uses lymphocytes (e.g., T and B cells) and antigen recognition molecules (e.g., antibodies, T-cell receptors).
Question 5 of 5
Adaptive immune system response typically takes how long?
Correct Answer: D
Rationale: The adaptive immune response, involving lymphocyte activation and proliferation, takes days to fully develop, unlike the rapid innate response.