A 16-year-old high school junior is brought to your clinic by his father. The teenager was taught in his health class at school to do monthly testicular self-examinations. Yesterday when he felt his left testicle it was enlarged and tender. He isn't sure if he has had burning with urination and he says he has never had sexual intercourse. He has had a sore throat, cough, and runny nose for the last 3 days. His past medical history is significant for a tonsillectomy as a small child. His father has high blood pressure and his mother is healthy. On examination you see a teenager in no acute distress. His temperature is 8 and his blood pressure and pulse are unremarkable. On visualization of his penis, he is uncircumcised and has no lesions or discharge. His scrotum is red and tense on the left and normal appearing on the right. Palpating his left testicle reveals a mildly sore swollen testicle. The right testicle is unremarkable. An examining finger is put through both inguinal rings, and there are no bulges with bearing down. His prostate examination is unremarkable. Urine analysis is also unremarkable. What abnormality of the testes does this teenager most likely have?

Correct Answer: A

Rationale: The correct answer is A: Acute orchitis. Orchitis is inflammation of the testicle that can cause testicular enlargement and tenderness. In this case, the teenager presents with a swollen and sore left testicle, which aligns with the symptoms of orchitis. The patient's history of upper respiratory symptoms suggests a viral infection, which can lead to orchitis. The normal prostate exam and urine analysis rule out prostatitis. Acute epididymitis typically presents with pain and swelling in the epididymis, not the testicle itself. Torsion of the spermatic cord would present with sudden, severe testicular pain and is an emergency requiring immediate surgical intervention.

Correct Answer: D

Rationale: The correct answer is D: It can protect against anogenital lesions. The HPV vaccine can protect against several types of HPV that are known to cause anogenital warts and lesions. This is based on scientific evidence from clinical trials. A: Ideally it should be administered within 3 years of first intercourse - This statement is not accurate. The HPV vaccine is recommended for both males and females between the ages of 9 and 26, regardless of sexual activity. B: It covers against almost every HPV type - This statement is incorrect. While the HPV vaccine covers the most common high-risk HPV types that cause cervical cancer, it does not cover against every HPV type. C: It can be used as adjuvant therapy in cervical cancer - This statement is incorrect. The HPV vaccine is primarily used as a preventive measure to reduce the risk of HPV infection and related health issues, not as a treatment for existing cervical cancer.

Correct Answer: C

Rationale: The pectinate or dentate line is the border between the anal canal and the rectum. This is true because it represents the transition between the endoderm-derived upper anal canal and the ectoderm-derived lower anal canal. It is an important anatomical landmark in colorectal surgery and in distinguishing different pathologies in the anal region. Choice A is incorrect because the pectinate or dentate line is not typically palpable. Choice B is incorrect as it does not demarcate areas supplied by different nervous systems. Choice D is incorrect as the pectinate or dentate line is visible on proctoscopic examination due to its distinct appearance.

Correct Answer: B

Rationale: The correct answer is B: Straight-leg raise. This test is used to assess for herniated disc by stretching the sciatic nerve. A positive test is indicated by reproduction of leg pain when the leg is raised between 30 to 70 degrees. This suggests nerve root irritation, common in herniated disc. A: Leg-length test - This test is used to assess for leg length discrepancy, not herniated disc. C: Tinel's test - This test is used to assess for nerve compression, typically in carpal tunnel syndrome, not specifically for herniated disc. D: Phalen's test - This test is used to assess for carpal tunnel syndrome, not herniated disc.

Correct Answer: B

Rationale: The correct answer is B (Pain) because pain is a common symptom in both inflammatory and non-inflammatory joint conditions. Tenderness, warmth, and redness are more specific to inflammatory joint problems. Tenderness indicates localized inflammation, warmth suggests increased blood flow and inflammation, and redness signifies dilated blood vessels and inflammation. Therefore, pain alone is less helpful in determining if a joint problem is inflammatory compared to the other symptoms.