A 16 y.o. boy from a countryside entered an educational establishment. Scheduled Manteux test revealed that the boy had negative reaction. What are the most reasonable actions in this case?

Correct Answer: C

Rationale: The correct answer is C: To perform serodiagnostics of tuberculosis. Rationale: The negative reaction to the Mantoux test indicates absence of TB infection. Performing serodiagnostics will further confirm the absence of active infection. This is important to rule out TB before considering vaccination or isolation measures. Summary: A: BCG vaccination is not necessary as the boy shows a negative reaction to the Mantoux test. B: Repeating the test in a month is unnecessary as the initial test already showed a negative reaction. D: Isolating the boy is not warranted as there is no evidence of active TB infection.

Correct Answer: B

Rationale: The correct answer is B: BCG vaccine. Bacille Calmette-Guérin (BCG) vaccine is used to prevent tuberculosis, which is caused by a bacterium related to anthrax. BCG vaccine can provide cross-protection against anthrax due to its similar mechanisms of action. STI live vaccine (choice A) is used for sexually transmitted infections, not anthrax. Salk vaccine (choice C) is used for polio, and Sabin's vaccine (choice D) is also for polio, not anthrax. Therefore, BCG vaccine is the most appropriate choice for preventing the spread of anthrax among animals in the countryside.

Correct Answer: A

Rationale: The correct answer is A: Corynebacterium diphtheriae. This bacterium causes diphtheria, characterized by a grayish pseudomembrane in the throat. The dark blue-staining rods with polar granules seen in microscopic examination are known as metachromatic granules, which are specific to Corynebacterium diphtheriae. Streptococcus pyogenes (choice B) causes strep throat but does not produce pseudomembranes. Haemophilus influenzae (choice C) can cause respiratory infections but does not typically present with a pseudomembrane. Neisseria gonorrhoeae (choice D) is a sexually transmitted bacterium and is not associated with the symptoms described.

Correct Answer: B

Rationale: The correct answer is B (Urethra). Resident microflora are typically found in various parts of the body where they establish a stable population without causing harm. The urethra is one of the locations where resident microflora are commonly present, helping to maintain a healthy microbial balance and prevent pathogenic bacteria from colonizing the area. In contrast, choices A, C, and D are not typical locations for resident microflora. Blood is normally sterile, the lungs have a different microbial environment due to their exposure to the external environment, and the cerebro-spinal fluid is also typically sterile to prevent infections in the central nervous system.

Correct Answer: A

Rationale: The correct answer is A because differential growth media, such as Endo agar and MacConkey agar, contain specific indicators or substrates that allow for the differentiation of microorganisms based on their metabolic properties. For example, Eosin methylene blue agar differentiates between lactose fermenting and non-fermenting bacteria based on color changes. Levine's formulation is selective for Gram-negative bacteria due to bile salts and crystal violet. In contrast, the other choices do not have specific indicators for differentiation among microorganisms. Lowenstein-Jensen and SS agar are selective media for mycobacteria and Salmonella/Shigella species, respectively. ACA and BPLS agar are selective but not differential, and Nutrient agar and Peptone water are general-purpose media without differential properties.

Correct Answer: C

Rationale: The correct answer is C: All answers are correct. Pneumonia can be caused by various pathogens, including Legionella pneumophila and Mycoplasma pneumoniae. Choice C is correct because both A and B are known causative agents of pneumonia. Choice D is incorrect because we know that Legionella pneumophila and Mycoplasma pneumoniae can cause pneumonia, so the statement "None of the above" is not accurate in this context.

Correct Answer: A

Rationale: The correct answer is A: Vibrio cholerae. 1. Vibrio cholerae is a Gram-negative, comma-shaped bacterium known to cause cholera. 2. Shigella dysenteriae causes dysentery, not cholera. 3. Salmonella typhi causes typhoid fever, not cholera. 4. Campylobacter jejuni causes gastroenteritis, not cholera. Therefore, based on the symptoms presented and the characteristics of the bacterium, Vibrio cholerae is the most likely microorganism.

Correct Answer: B

Rationale: The correct answer is B: As a result of mosquito's bites. Sleeping sickness, also known as African trypanosomiasis, is caused by the parasite Trypanosoma transmitted by tsetse flies, not mosquitoes. Tsetse flies are primarily found in Africa, not South America. Choice A is incorrect as bug bites do not transmit sleeping sickness. Choice C is incorrect as contaminated fruits and vegetables do not transmit the disease. Choice D is incorrect as dirty hands do not play a role in the transmission of sleeping sickness.

Correct Answer: C

Rationale: The correct answer is C: leg swelling. Endocarditis is an infection of the inner lining of the heart chambers and valves. Symptoms typically include fever, chills, weight loss, and muscle aches due to the body's immune response to the infection. Leg swelling is not a common symptom of endocarditis. It may occur in conditions like heart failure but is not directly associated with endocarditis. Therefore, choice C is the correct answer. Choices A, B, and D are incorrect because fever and chills, weight loss, and muscle aches are commonly seen in endocarditis due to the systemic inflammatory response to the infection.