A 15-year-old boy with rheumatoid arthritis, on quinine for 6 months, presented with fever, aphthous stomatitis, and fatigue for the last 5 days. His absolute neutrophil count (ANC) was 700/μL. The MOST next appropriate therapeutic measure to be done when quinine withdrawal fails to improve neutropenia is

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Pediatric Immunization NCLEX Questions Questions

Question 1 of 5

A 15-year-old boy with rheumatoid arthritis, on quinine for 6 months, presented with fever, aphthous stomatitis, and fatigue for the last 5 days. His absolute neutrophil count (ANC) was 700/μL. The MOST next appropriate therapeutic measure to be done when quinine withdrawal fails to improve neutropenia is

Correct Answer: D

Rationale: G-CSF stimulates neutrophil production, effectively treating drug-induced neutropenia unresponsive to withdrawal.

Question 2 of 5

Which of the following is a messenger that mediates the connection between the innate and adaptive immune systems?

Correct Answer: D

Rationale: Cytokines are signaling molecules that bridge innate and adaptive immunity by facilitating communication, such as activating lymphocytes after innate detection of pathogens.

Question 3 of 5

Which of the following components of the innate immune system involves recognition molecules such as mannan-binding lectin (MBL) for bacteria with mannose on the surface?

Correct Answer: B

Rationale: The complement system uses MBL to recognize mannose on bacterial surfaces, triggering a cascade to eliminate pathogens.

Question 4 of 5

Macrophages

Correct Answer: A

Rationale: Macrophages perform phagocytosis, kill bacteria, and present antigens to T cells, key roles in innate immunity.

Question 5 of 5

Eventual elimination of antigen

Correct Answer: C

Rationale: The effector phase is when activated immune cells eliminate the antigen.

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